利用随时间变化的光子迁移的频域测量来确定散射介质中吸收体的位置。
Localization of absorbers in scattering media by use of frequency-domain measurements of time-dependent photon migration.
作者信息
Sevick E M, Frisoli J K, Burch C L, Lakowicz J R
出版信息
Appl Opt. 1994 Jun 1;33(16):3562-70. doi: 10.1364/AO.33.003562.
Abstract
Frequency-domain studies of time-dependent light propagation in tissuelike phantoms that contain optical heterogeneities are described. Specifically the phase shift and amplitude modulation of reemergent light were measured when illuminated by an amplitude-modulated light source. Changes in the phase angle and the extent of modulation revealed the presence of a light-absorbing object. Furthermore the magnitude and direction of these changes were sensitive to the absorber depth and the light modulation frequency in a manner that could be used to infer the location of the heterogeneity. These data suggest the feasibility of optical imaging by frequency-domain methods.
摘要
描述了对包含光学不均匀性的类组织模型中随时间变化的光传播进行的频域研究。具体而言，当用振幅调制光源照射时，测量了出射光的相移和振幅调制。相角的变化和调制程度揭示了光吸收物体的存在。此外，这些变化的大小和方向对吸收体深度和光调制频率敏感，其方式可用于推断不均匀性的位置。这些数据表明了通过频域方法进行光学成像的可行性。
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