Lipozenčić Jasna, Bukvić Mokos Zrinka
University Hospital Center Zagreb , Department of Dermatology and Venereology, School of Medicine, University of Zagreb, Šalata 4, Zagreb, Croatia.
Acta Dermatovenerol Croat. 2010;18(3):176-80.
Skin aging includes intrinsic aging, a universal and inevitable process attributable to the passage of the time alone; and photoaging, changes attributable to chronic sun exposure, which are neither universal nor inevitable. The major clinical features of aging skin include xerosis, laxity, wrinkles, slackness, and the occurrence of benign neoplasms such as seborrheic keratoses and cherry angiomas. Photoaging is characterized by dryness (roughness), actinic keratoses, irregular pigmentation (freckling, lentigines, guttate hypomelanosis, persistent hyperpigmentation), wrinkling, stellate pseudoscars, elastosis (fine nodularity and/or coarseness), inelasticity, telangiectasia, venous lakes, purpura (easy bruising), comedones (maladie de Favre et Racouchot) and sebaceous hyperplasia. Current antiaging therapy consists of lasers, intense pulsed light as well as fillers, neurotoxins, radiofrequency, microdermabrasion and chemical peeling. Over the last 50 years, lasers applications in dermatology have become more specific and often irreplaceable. In this manuscript laser resurfacing and laser therapy of vascular and pigmented lesions of aging skin will be overviewed. Current trends show an increase in the number of nonablative and fractional resurfacing procedures because they are followed by less intense side effects and faster recovery rates compared to ablative laser rejuvenation, although producing mild improvement.
皮肤老化包括自然老化,这是一个仅由时间推移导致的普遍且不可避免的过程;以及光老化,即由长期日晒引起的变化,这种情况既不普遍也非不可避免。老化皮肤的主要临床特征包括皮肤干燥、松弛、皱纹、皮肤下垂,以及出现脂溢性角化病和樱桃状血管瘤等良性肿瘤。光老化的特征表现为皮肤干燥(粗糙)、光化性角化病、色素沉着不规则(雀斑、雀斑样痣、点滴状色素减退、持续性色素沉着)、皱纹、星状假性瘢痕、弹性组织变性(细微结节和/或粗糙)、缺乏弹性、毛细血管扩张、静脉湖、紫癜(易出现瘀伤)、粉刺(法夫尔-拉库肖病)和皮脂腺增生。目前的抗老化治疗方法包括激光、强脉冲光以及填充剂、神经毒素、射频、微晶磨皮和化学剥脱术。在过去50年里,激光在皮肤科的应用变得更加精准,且常常不可替代。在本手稿中,将概述激光换肤以及对老化皮肤血管性和色素性病变的激光治疗。当前的趋势表明,非剥脱性和分次换肤手术的数量有所增加,因为与剥脱性激光嫩肤相比,它们产生的副作用较轻,恢复速度更快,尽管改善效果较为轻微。