McLean Hospital, 115 Mill St., Mailstop 226, Belmont, MA 02478, USA.
Psychiatr Serv. 2010 Oct;61(10):1000-5. doi: 10.1176/ps.2010.61.10.1000.
This study examined changes in possession of guideline-recommended medication among three groups of New York State Medicaid enrollees with severe mental illness: those who received an involuntary outpatient commitment order, voluntary enhanced services, or neither of these interventions.
An observational study was conducted with New York State Medicaid claims data for enrollees with bipolar, schizophrenia, or schizoaffective disorders in New York City, Long Island, and the Hudson River regions from 2000 to 2005 (N=7,762). With adjustment for clinical and demographic characteristics, logistic regression models predicted the probability of a monthly medication possession ratio (MPR) ≥ 80% for medications recommended by expert guidelines or by the U.S. Food and Drug Administration for the indicated psychiatric diagnosis. Separate models were fit by region and for patients who ever received assisted outpatient treatment (AOT), voluntary enhanced services but never AOT, or neither treatment.
In all three regions, for all three groups, the predicted probability of an MPR ≥ 80% improved over time (AOT improved by 31-40 percentage points, followed by enhanced services, which improved by 15-22 points, and "neither treatment," improving 8-19 points). Some regional differences in MPR trajectories were observed.
After New York implemented AOT and increased community resources for enhanced services, guideline-recommended medication possession improved among Medicaid enrollees with severe mental illness--even among those who never received these interventions or services. However, further study is needed to understand why there were different regional trajectories and why some groups did not gain similarly across regions.
本研究考察了三组纽约州医疗补助计划(Medicaid)严重精神疾病患者中,符合指南推荐的药物拥有情况的变化:接受非自愿门诊强制治疗令、自愿强化服务或两者均未接受的患者。
对纽约市、长岛和哈德逊河地区 2000 年至 2005 年间患有双相情感障碍、精神分裂症或分裂情感性障碍的纽约州 Medicaid 参保者的医疗保险索赔数据进行了一项观察性研究(N=7762)。通过调整临床和人口统计学特征,逻辑回归模型预测了每月药物拥有率(MPR)≥80%的可能性,即符合专家指南或美国食品和药物管理局(FDA)推荐的用于特定精神科诊断的药物。分别为三个地区和接受过辅助门诊治疗(AOT)、自愿强化服务但从未接受过 AOT 或两者均未接受治疗的患者建立了单独的模型。
在所有三个地区,对于所有三组患者,MPR≥80%的预测概率随时间推移而提高(AOT 提高了 31-40 个百分点,其次是强化服务,提高了 15-22 个百分点,而“两者均未接受治疗”提高了 8-19 个百分点)。观察到了一些地区 MPR 轨迹的差异。
在纽约州实施 AOT 并增加社区强化服务资源后,即使是那些从未接受过这些干预或服务的 Medicaid 参保者,符合指南推荐的药物拥有情况也有所改善。然而,仍需要进一步研究以了解为什么存在不同的地区轨迹,以及为什么有些群体在不同地区没有获得类似的改善。