Ming-Kai Chen, Ting Zhou
Department of Gastroenterology, Renmin Hospital of Wuhan University, Wuhan City, HuBei Province, People's Republic of China.
South Med J. 2010 Nov;103(11):1163-6. doi: 10.1097/SMJ.0b013e3181f1eda1.
Primary hyperparathyroidism (PHPT) is characterized by inappropriate secretion of parathyroid hormone (PTH). The proportion of PHPT with asymptomatic or nontypical symptoms is continuously increasing. PHPT typically affects elderly women, and it is characterized by few symptoms or complications. We explored a case of a 77-year-old woman with previously undiagnosed PHPT who presented first with palpitation and chest distress, and then had the symptoms of intractable nausea and vomiting. The initial laboratory investigations revealed normal calcium levels. Further examination showed serum calcium and PTH were elevated. In order to attach importance to PHPT in asymptomatic patients or patients with nontypical symptoms, related literature was reviewed. Finally the methods of treatment of PHPT in elderly patients were discussed.
原发性甲状旁腺功能亢进症(PHPT)的特征是甲状旁腺激素(PTH)分泌异常。无症状或非典型症状的PHPT比例正在持续增加。PHPT通常影响老年女性,其特点是症状或并发症较少。我们探讨了一例77岁先前未被诊断出患有PHPT的女性病例,该患者最初表现为心悸和胸闷,随后出现顽固性恶心和呕吐症状。最初的实验室检查显示钙水平正常。进一步检查发现血清钙和PTH升高。为了重视无症状或有非典型症状患者的PHPT,我们查阅了相关文献。最后讨论了老年患者PHPT的治疗方法。