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舍尼通治疗慢性非细菌性前列腺炎疗效与安全性的临床随机对照试验

[A comparative clinical randomized trial of cernilton efficacy and safety in patients with chronic abacterial prostatitis].

作者信息

Apolikhin O I, Aliaev Iu G, Sivkov A V, Vinarov A Z, Oshchepkov V N, Keshishev N G, Bedretdinova D A, Akhvlediani N D

出版信息

Urologiia. 2010 Jan-Feb(1):29-34.

PMID:20891044
Abstract

The trial of efficacy and safety of two doses of the drug cernilton in patients with chronic abacterial prostatitis made in the Research Institute of Urology and I.M. Sechenov Medical Academy in 2008 gave evidence for subjective (NIH-CPSI, Sex-4, IPSS and other scales, QOL) and objective (leucocyte count in prostatic secretion) pronounced anti-inflammatory effects of the drug which persist for at least 6 months. Comparison of the two doses of cernilton showed significant differences in subjective response of the patients (NIH-CPSI and Symptom Frequency Scale). Cernilton is recommended as a medication of choice for treatment of patients with chronic abacterial prostatitis.

摘要

2008年,泌尿外科研究所和谢马什克夫医学科学院对两剂药“舍尼通”治疗慢性非细菌性前列腺炎患者的疗效和安全性进行了试验,结果表明该药具有显著的主观(美国国立卫生研究院慢性前列腺炎症状指数、性健康量表、国际前列腺症状评分等量表、生活质量)和客观(前列腺分泌物白细胞计数)抗炎作用,且至少持续6个月。对两剂舍尼通的比较显示,患者的主观反应(美国国立卫生研究院慢性前列腺炎症状指数和症状频率量表)存在显著差异。舍尼通被推荐为治疗慢性非细菌性前列腺炎患者的首选药物。

相似文献

1
[A comparative clinical randomized trial of cernilton efficacy and safety in patients with chronic abacterial prostatitis].舍尼通治疗慢性非细菌性前列腺炎疗效与安全性的临床随机对照试验
Urologiia. 2010 Jan-Feb(1):29-34.
2
[Use of cernilton in the therapy of prostatic adenoma and chronic prostatitis].
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[Cernilton in the treatment of prostatic adenoma and chronic prostatitis].
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A pollen extract (Cernilton) in patients with inflammatory chronic prostatitis-chronic pelvic pain syndrome: a multicentre, randomised, prospective, double-blind, placebo-controlled phase 3 study.花粉提取物(舍尼通)用于炎性慢性前列腺炎-慢性盆腔疼痛综合征患者:一项多中心、随机、前瞻性、双盲、安慰剂对照的3期研究。
Eur Urol. 2009 Sep;56(3):544-51. doi: 10.1016/j.eururo.2009.05.046. Epub 2009 Jun 3.
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Treatment of chronic prostatitis/chronic pelvic pain syndrome category IIIA with Serenoa repens plus selenium and lycopene (Profluss) versus S. repens alone: an Italian randomized multicenter-controlled study.锯叶棕果实提取物联合硒和番茄红素(Profluss)与单独使用锯叶棕果实提取物治疗ⅢA型慢性前列腺炎/慢性盆腔疼痛综合征:一项意大利随机多中心对照研究
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Eviprostat has an identical effect compared to pollen extract (Cernilton) in patients with chronic prostatitis/chronic pelvic pain syndrome: a randomized, prospective study.爱普列特与花粉提取物(舍尼通)对慢性前列腺炎/慢性盆腔疼痛综合征患者具有相同疗效:一项随机前瞻性研究。
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[A long-term therapeutic experience with Cernilton in chronic prostatitis].[舍尼通治疗慢性前列腺炎的长期治疗经验]
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[A Japanese version of the National Institutes of Health Chronic Prostatitis Symptom Index (NIH-CPSI, Okayama version) and the clinical evaluation of cernitin pollen extract for chronic non-bacterial prostatitis].[日本版美国国立卫生研究院慢性前列腺炎症状指数(NIH-CPSI,冈山版)及舍尼通花粉提取物治疗慢性非细菌性前列腺炎的临床评估]
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