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[慢性淋巴细胞白血病患者中性粒细胞的整体四氮唑活性]

[The integral tetrazolium activity of the neutrophils in patients with chronic lympholeukemia].

作者信息

Gaĭdukova S N

出版信息

Vrach Delo. 1990 Dec(12):86-8.

PMID:2089816
Abstract

A study is presented of the functional activity of peripheral blood neutrophils in 58 patients with chronic lympholeucosis, 27 patients with purulent-inflammatory diseases of the nasopharynx. Patients with chronic lympholeucosis were subdivided in two groups: with infectious complications and without these complications. The reaction of reduction nitroblue tetrazolium was used (Park method in modification by Shubich and Mednikova). The integral tetrazolium activity of neutrophils was determined according to a formula proposed by Drannik and Kovalev. Results indicate that determination of the functional activity of neutrophils has a high information value, allows to evaluate the potentialities of the immune system of the body and plan ways of correction.

摘要

本文介绍了对58例慢性淋巴细胞白血病患者及27例鼻咽部化脓性炎症疾病患者外周血中性粒细胞功能活性的研究。慢性淋巴细胞白血病患者被分为两组:有感染并发症组和无感染并发症组。采用还原硝基蓝四氮唑反应(舒比奇和梅德尼科娃改良的帕克法)。根据德兰尼克和科瓦列夫提出的公式测定中性粒细胞的四氮唑积分活性。结果表明,测定中性粒细胞的功能活性具有很高的信息价值,有助于评估机体免疫系统的潜力并规划纠正方法。

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