Tychmanowicz K, Czernicki Z, Czosnyka M, Pawłowski G, Uchman G
Department of Neurosurgery, Medical Research Centre, Polish Academy of Sciences, Warsaw.
Acta Neurochir Suppl (Wien). 1990;51:233-5. doi: 10.1007/978-3-7091-9115-6_78.
Saggital sinus occlusion was produced in cats. The intracranial volume-pressure relations were studied using the lumbar infusion tests. Right after occlusion ICP rised from 7.1 +/- 1.8 to 12.4 +/- 4.1 mmHg. The values of outflow resistance and volume-pressure response increased also and remained significantly unchanged with only slight decrease of the volume-pressure response. The morphometric study of the surface veins showed the dilatation of the veins draining to the occluded saggital sinus for about 10-20%. No signs of the blood-brain barrier disruption were observed.
在猫身上造成矢状窦闭塞。使用腰椎灌注试验研究颅内体积 - 压力关系。闭塞后即刻，颅内压从7.1±1.8 mmHg升至12.4±4.1 mmHg。流出阻力和体积 - 压力反应的值也增加，并且除了体积 - 压力反应略有下降外，其余均保持显著不变。对表面静脉的形态学研究显示，引流至闭塞矢状窦的静脉扩张约10 - 20%。未观察到血脑屏障破坏的迹象。
