Torné Cachot J, Soriano Giménez J C, Tomás Vecina S, Miralles Basseda R, Garcés Jarque J M
Servicio de Medicina Interna, Hospital del Mar, Universidad Autónoma de Barcelona.
Med Clin (Barc). 1990 Nov 3;95(15):568-71.
This reports the analysis of an epidemiologic study of intravascular cannula bacteriemia (ICB) in a Barcelona university hospital. There were 91 episodes of ICB representing the 26.7% of the total hospital bacteriemia. In 60.6% of ICB the diagnosis was made in an intensive care area. The most common microorganisms were Staphylococcus epidermidis (27.8%), Pseudomonas aeruginosa (18.5%), and Staphylococcus aureus (14.4%). Intravascular cannulae with higher incidence of bacteriemia were the central venous catheters (55%) and the arterial lines (29%). Bacteriemia produced by arterial lines had short free period interval (7.7 days) and in 80% of the cases were produced by Gram negative bacteria whereas that bacteriemia produced by central venous catheters had a long free period (11.2 days) and the most frequent agents were Gram positive bacteria. The overall mortality was 17% and that attributed to the infection 6%. An age above 65 years had a mortality rate of 33% and was identified as the only significant prognostic factor (p less than 0.001). The mean hospitalization period was 49.9 days and the cost of the treatment 830.000 ptas/patient.
本文报告了巴塞罗那一家大学医院对血管内插管菌血症(ICB)的一项流行病学研究分析。共有91例ICB发作,占医院菌血症总数的26.7%。在60.6%的ICB病例中,诊断是在重症监护区做出的。最常见的微生物是表皮葡萄球菌(27.8%)、铜绿假单胞菌(18.5%)和金黄色葡萄球菌(14.4%)。菌血症发生率较高的血管内插管是中心静脉导管(55%)和动脉导管(29%)。动脉导管引起的菌血症游离期短(7.7天),80%的病例由革兰氏阴性菌引起;而中心静脉导管引起的菌血症游离期长(11.2天),最常见的病原体是革兰氏阳性菌。总死亡率为17%,感染导致的死亡率为6%。65岁以上患者的死亡率为33%,被确定为唯一显著的预后因素(p小于0.001)。平均住院时间为49.9天,每位患者的治疗费用为830,000比塞塔。