Muldoon S M, Janssens W J, Verbeuren T J, Vanhoutte P M
Br J Anaesth. 1977 Mar;49(3):211-6. doi: 10.1093/bja/49.3.211.
Concentrations of droperidol which caused a shift to the right of the dose-response curve to noradrenaline in the pulmonary artery and the saphenous vein of the dog did not affect myogenic activation by K+; they did not inhibit spontaneous activity of portal-mesenteric veins. Droperidol inhibited the contractile response to nerve stimulation, but did not affect the evoked release of 3H-noradrenaline. These experiments indicate that the vasodilator properties of smaller doses of droperidol are a result of its ability to block alpha-adrenergic receptors.
导致犬肺动脉和隐静脉中去甲肾上腺素剂量-反应曲线右移的氟哌利多浓度，并不影响K⁺引起的肌源性激活；它们不抑制门静脉-肠系膜静脉的自发活动。氟哌利多抑制对神经刺激的收缩反应，但不影响3H-去甲肾上腺素的诱发释放。这些实验表明，较小剂量氟哌利多的血管舒张特性是其阻断α-肾上腺素能受体能力的结果。
