Goubau P, Carton H, Kazadi K, Muya K W, Desmyter J
Department of Microbiology, Rega Institute, Leuven, Belgium.
Trans R Soc Trop Med Hyg. 1990 Jul-Aug;84(4):577-9. doi: 10.1016/0035-9203(90)90046-h.
In Lisala (Equateur region, Zaire), where a cluster of tropical spastic paraparesis/HTLV-1 associated myelopathy (TSP/HAM) was described, 28/200 (14%) out-patients and hospital personnel were HTLV antibody positive. No differences in prevalences were observed between out-patients and hospital personnel or between ethnic groups. The annual attack rate of TSP/HAM is estimated at 0.15-0.3 per 1000 infected. The ethnic and familial clustering of TSP/HAM together with the high attack rate suggests the presence of co-factors for the progression to disease. This high prevalence of HTLV antibodies contrasts with the low prevalence in another part of the Equateur region.
在利萨拉（扎伊尔赤道地区），曾有热带痉挛性截瘫/人嗜T淋巴细胞病毒1型相关脊髓病（TSP/HAM）聚集性病例的报道，200名门诊患者及医院工作人员中有28人（14%）HTLV抗体呈阳性。门诊患者与医院工作人员之间以及不同种族群体之间的患病率无差异。据估计，TSP/HAM的年发病率为每1000名感染者中有0.15 - 0.3例。TSP/HAM在种族和家族中的聚集现象以及高发病率表明存在促使疾病进展的协同因素。HTLV抗体的高患病率与赤道地区另一部分的低患病率形成对比。
