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[神经皮肤黑素沉着症与脑黑色素瘤]

[Neurocutaneous melanosis and melanoma of the brain].

作者信息

Jandro-Santel D, Popović-Grle S, Cvitanović L, Hlavka V, Kalousek M, Lupret V

机构信息

Zavoda za neuropatologiju Klinickog bolnickog centra, Zagrebu.

出版信息

Acta Med Iugosl. 1990;44(4):275-83.

PMID:2091433
Abstract

A case of neuro-cutaneous melanoma, in the course of which a bifocal melanoma of the cerebral hemisphere had developed, was used as a natural model for the study of the relation between tumorous and non-tumorous elements. The need is pointed out for the definition of such a cutaneous-meningeal syndrome before the development of a neoplasm. As tumours develop from the cells defining leptomeningeal melanosis, the possibility of a neuroradiological diagnosis of this process is accentuated, primarily by a minute examination of the sites characteristic of the disease. A premorbid detection of all such cases is imperative in order to introduce an early anti-tumour treatment.

摘要

一例神经皮肤黑色素瘤患者,其大脑半球出现了双灶性黑色素瘤,被用作研究肿瘤性和非肿瘤性成分之间关系的自然模型。文中指出,在肿瘤发生之前定义这种皮肤-脑膜综合征的必要性。由于肿瘤由界定软脑膜黑色素沉着症的细胞发展而来,通过对该病特征部位进行细致检查,神经放射学诊断该过程的可能性得以增强。为了尽早开展抗肿瘤治疗,对所有此类病例进行病前检测势在必行。

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