Roselló Sastre E, Cerda Nicolás M, Barcia Mariño C
Departamento de Patología Neuropatología, Facultad de Medicina, Valencia.
Arch Neurobiol (Madr). 1990 Nov-Dec;53(6):227-32.
We present a case of cerebral gangliocytoma placed on the right frontal lobe in a young adult, analyzing its morphological and clinical features. The immunohistochemical study defines it as a tumor with a neuronal population NSE and NFP positive, and a glial population with positivity for the GFAP. We emphasize the presence of neurosecretion in the mature neurones, typified by the positivity to the sinaptophisine and VIP. In the discussion we compare our immunohistochemical results, analyzing the histogenesis of this rare neoplasm.
我们报告一例年轻成人右额叶的脑节细胞胶质瘤病例,并分析其形态学和临床特征。免疫组织化学研究将其定义为一种肿瘤,其中神经元成分NSE和NFP呈阳性,胶质成分GFAP呈阳性。我们强调成熟神经元中存在神经分泌现象,以突触素和血管活性肠肽呈阳性为典型表现。在讨论中,我们比较了免疫组织化学结果,分析了这种罕见肿瘤的组织发生。