合成富含组氨酸肽对牙龈卟啉单胞菌381血凝作用的抑制效果
Inhibitory effects of synthetic histidine-rich peptides on haemagglutination by Bacteroides gingivalis 381.
作者信息
Murakami Y, Takeshita T, Shizukuishi S, Tsunemitsu A, Aimoto S
机构信息
Department of Preventive Dentistry, Osaka University Faculty of Dentistry, Japan.
出版信息
Arch Oral Biol. 1990;35(9):775-7. doi: 10.1016/0003-9969(90)90103-h.
PMID:2091597
Abstract
The haemagglutinating activity of Bacteroides gingivalis 381 was significantly inhibited by the synthetic peptide, Asp-Ser-His-Ala-Lys-Arg-His-His-Gly-Tyr-Lys-Arg-Lys-Phe-His- Glu-Lys-His-His-Ser-His-Arg-Gly-Tyr. However, bradykinin potentiator C, which does not contain cationic amino acids such as L-histidine, L-arginine and L-lysine, had no inhibitory effect.
摘要
牙龈拟杆菌381的血凝活性受到合成肽天冬氨酸-丝氨酸-组氨酸-丙氨酸-赖氨酸-精氨酸-组氨酸-组氨酸-甘氨酸-酪氨酸-赖氨酸-精氨酸-赖氨酸-苯丙氨酸-组氨酸-谷氨酸-赖氨酸-组氨酸-组氨酸-丝氨酸-组氨酸-精氨酸-甘氨酸-酪氨酸的显著抑制。然而，不包含L-组氨酸、L-精氨酸和L-赖氨酸等阳离子氨基酸的缓激肽增强肽C没有抑制作用。
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