Six-year follow up of phenylalanine intakes and plasma phenylalanine concentrations.

The daily Phe intakes of normally growing 1- to 6-year-old treated PKU patients were evaluated. The children received protein in amounts that varied from 2.26 +/- 0.47 g/kg body weight per day (mean +/- SD) at the age of 6 to 1.81 +/- 0.35 at the age of 72 months. Mean Phe intakes declining from 34 +/- 7 at the age of 6 months to 15 +/- 5 mg/kg body weight per day at the age of 72 months were required to maintain mean median plasma Phe levels around 6.0 mg/dl.