Sustained profile of transmitted drug resistance mutations for more than 10 years in an HIV type 1-infected patient.
作者信息
Martínez-Prats Lorena, Luczkowiak Joanna, Gutiérrez Francisca, Zurita Sagrario, Fiorante Silvana, Llenas-García Jara, Pulido Federico, Delgado Rafael
机构信息
Hospital Universitario 12 de Octubre, Madrid, Spain.
出版信息
AIDS Res Hum Retroviruses. 2011 Jan;27(1):41-5. doi: 10.1089/aid.2010.0104. Epub 2010 Oct 4.
PMID:20919922
Abstract
We present an HIV-1-infected patient with a profile of transmitted drug resistance (RT M41L, E44D, V118I, L210W, T215D) sustained during more than 10 years in the absence of treatment. Clonal analysis of different plasma and cellular samples within this period did not reveal any reversion to the wild-type genotype.
摘要
Zotero 插件