脑恶性胶质瘤中淋巴细胞浸润的预后意义

Prognostic significance of lymphoid infiltration in cerebral malignant gliomas.

作者信息

Bucciero A, Vizioli L, Giamundo A, Villano M, Quaglietta P, Cerillo A

机构信息

Division of Neurotraumatology, 2nd School of Medicine, University of Naples, Italy.

出版信息

J Neurosurg Sci. 1990 Apr-Jun;34(2):145-8.

PMID:2092095

Abstract

Data concerning a study on lymphoid infiltration in 61 cerebral malignant gliomas are reported. Lymphoid cellular infiltrates were found in 28 cases (45.9%): 8 (13.1%) with marked and 20 (32.8%) with slight infiltration; the remaining 33 cases (54.1%) did not exhibit lymphoid infiltration. The mean survival time (+/- standard deviation) of patients harboring gliomas with marked lymphoid infiltration was 20.5 (+/-19.9) months, and that of patients with slight lymphoid infiltration in their glioma was 10.3 (+/- 7.5) months; those patients having gliomas without lymphoid cellular infiltrates showed a mean survival time (+/- standard deviation) of 7.2 (+/-6.1) months.

摘要

报告了一项关于61例脑恶性胶质瘤中淋巴细胞浸润的研究数据。在28例（45.9%）中发现淋巴细胞浸润：8例（13.1%）为明显浸润，20例（32.8%）为轻度浸润；其余33例（54.1%）未表现出淋巴细胞浸润。胶质瘤伴有明显淋巴细胞浸润的患者平均生存时间（±标准差）为20.5（±19.9）个月，胶质瘤伴有轻度淋巴细胞浸润的患者平均生存时间为10.3（±7.5）个月；那些胶质瘤无淋巴细胞浸润的患者平均生存时间（±标准差）为7.2（±6.1）个月。