Villiger Martin, Lasser Theo
Laboratoire d’Optique Biomédicale, Ecole Polytechnique Fédérale de Lausanne, Station 17, CH-1015 Lausanne, Switzerland.
J Opt Soc Am A Opt Image Sci Vis. 2010 Oct 1;27(10):2216-28. doi: 10.1364/JOSAA.27.002216.
In this work we present a model for image formation in optical coherence microscopy. In the spectral domain detection, each wavenumber has a specific coherent transfer function that samples a different part of the object's spatial frequency spectrum. The reconstruction of the tomogram is usually accurate only in a short depth of field. Using numerical simulations based on the developed model, we identified two distinct mechanisms that influence the signal of out-of-focus sample information. Besides the lateral blurring induced through defocusing, an additional axial envelope contributing equally to the signal degradation was found.
在这项工作中,我们提出了一种光学相干显微镜中的图像形成模型。在光谱域检测中,每个波数都有一个特定的相干传递函数,该函数对物体空间频谱的不同部分进行采样。层析成像的重建通常仅在短景深内是准确的。通过基于所开发模型的数值模拟,我们确定了两种影响离焦样本信息信号的不同机制。除了通过散焦引起的横向模糊外,还发现了一个对信号退化同样有贡献的额外轴向包络。