3rd Medical Clinic, University of Medicine and Pharmacy, Cluj Napoca, Romania.
J Gastrointestin Liver Dis. 2010 Sep;19(3):329-32.
We present the case of a female patient diagnosed with colonic Crohn's disease, having a clinical evolution with many recurrences and in whom conventional therapy had failed. The patient was admitted in our department 4 years after the onset of the disease, with an altered general state, diarrhea, malnutrition, fever and fecaloid vaginal discharge. Investigations classified the patient in a severe activity flare of Crohn's disease (CDAI 329), complicated with a rectovaginal fistula. Infliximab therapy was initiated. The evolution was rapidly favorable and the fistula closed after 4 weeks of therapy.
我们报告一例女性克罗恩病患者，临床表现为多次复发，常规治疗失败。患者在发病 4 年后入我院，表现为一般状况改变、腹泻、营养不良、发热和粪便样阴道排液。检查将患者分类为克罗恩病重度活动期（CDAI329），并伴有直肠阴道瘘。开始使用英夫利昔单抗治疗。治疗 4 周后，病情迅速好转，瘘管闭合。
