Syrian Center for Tobacco Studies, Faculty of Medicine, University of Aleppo, Aleppo, Syria.
J Diabetes. 2010 Jun;2(2):85-91. doi: 10.1111/j.1753-0407.2009.00063.x. Epub 2009 Nov 2.
Type 2 diabetes mellitus (T2DM) is considerable public health problem, but data on the prevalence and correlates of T2DM in Syria are scarce. The aim of the present study was to establish reliable estimates of the prevalence of T2DM in Syria.
A cross-sectional, population-based survey was conducted in Aleppo, Syria (population 2.5 million), in 2006. The study was conducted on a random sample of 1168 subjects ≥25 years of age (47.7% men; mean age 44.7 ± 12.7 years). Information regarding a personal history of diabetes and other risk factors was collected, followed by measurement of weight, height, and the waist:hip ratio (WHR). Of the 1168 participants, 806 provided fasting blood samples that were analyzed for fasting plasma glucose (FPG) and HbA1c.
The prevalence of T2DM based on FPG ≥126 mg/dL and HbA1c ≥6.5% was 15.6% (11.2% self-reported; 5.0% diagnosed) and 14.8%, respectively. The prevalence of impaired fasting glucose (FPG ≥110 and <126 mg/dL) was 8.6%. There was a significant positive association between T2DM and age, WHR, a family history of T2DM, and body mass index (BMI) and an inverse association between T2DM and physical activity (P < 0.01 for all). Multivariate analysis showed that age, BMI, WHR, and a family history of T2DM were the most important factors associated with T2DM. Only 16.7% of treated cases of T2DM were under control (i.e. HbA1c <7%).
Based on the results obtained in our sample, T2DM is widespread in Syria. Many of those with T2DM are unaware of their disease and most have unsatisfactory control of their disease.
2 型糖尿病（T2DM）是一个相当严重的公共卫生问题，但有关叙利亚 T2DM 的患病率和相关因素的数据却很少。本研究的目的是确定叙利亚 T2DM 的患病率的可靠估计值。
2006 年在叙利亚阿勒颇进行了一项横断面、基于人群的调查。该研究对≥25 岁的 1168 名随机样本（47.7%为男性；平均年龄 44.7 ± 12.7 岁）进行了调查。收集了有关糖尿病个人史和其他危险因素的信息，随后测量了体重、身高和腰围：臀围比（WHR）。在 1168 名参与者中，有 806 名提供了空腹血样，用于分析空腹血糖（FPG）和 HbA1c。
根据 FPG≥126mg/dL 和 HbA1c≥6.5%，T2DM 的患病率分别为 15.6%（11.2%为自我报告；5.0%为诊断）和 14.8%。空腹血糖受损（FPG≥110 且 <126mg/dL）的患病率为 8.6%。T2DM 与年龄、WHR、T2DM 家族史和体重指数（BMI）呈显著正相关，与体力活动呈负相关（P<0.01 均）。多变量分析显示，年龄、BMI、WHR 和 T2DM 家族史是与 T2DM 最相关的最重要因素。只有 16.7%的 T2DM 治疗病例得到控制（即 HbA1c<7%）。
根据我们样本中获得的结果，T2DM 在叙利亚很普遍。许多患有 T2DM 的人不知道自己的疾病，而且大多数人的疾病控制都不理想。
