Section of Infectious diseases, Division of Pulmonology, Department of Medicine, Medical University of Graz, Graz, Austria.
Wien Klin Wochenschr. 2010 Oct;122 Suppl 3:94-6. doi: 10.1007/s00508-010-1445-7.
Ascariasis is the most common helminthic infection, with an estimated worldwide prevalence of 25%. The estimated mortality ranges from 0.8 to 1%. Second stage larvae pass through the intestinal wall and migrate via the portal vein system to the liver and then proceed to the lungs, where they may produce pneumonia and eosinophilia. Symptoms include wheezing, dyspnea, nonproductive cough, hemoptysis, and fever. Two cases of pulmonary ascariasis in Austrian males are reported. Both patients presented with dyspnea, nonproductive cough, fever, and eosinophilia (19 and 26%). One patient additionally had pulmonary infiltrates. Recent travel history was unremarkable in both individuals. Serology for Ascaris was positive twice in both patients, while microscopic examination of stool was negative for helminthic ova. Extensive diagnostic procedures were performed to rule out possible differentials for the patients symptoms. Both patients responded well to antiparasitic treatment with albendazole 400 mg and mebendazole 100 mg q12h for 3 days, respectively. This report highlights the importance of considering parasitic infection in patients presenting with eosinophilia and pulmonary symptoms also in Austria.
蛔虫病是最常见的寄生虫感染,全球估计患病率为 25%。死亡率估计在 0.8%至 1%之间。第二期幼虫穿过肠壁,通过门静脉系统迁移到肝脏,然后进入肺部,在肺部可能引起肺炎和嗜酸性粒细胞增多症。症状包括喘息、呼吸困难、干咳、咯血和发热。报告了奥地利两名男性的肺部蛔虫病病例。两名患者均出现呼吸困难、干咳、发热和嗜酸性粒细胞增多症(19%和 26%)。一名患者还出现肺部浸润。两名患者的寄生虫血清学检查均两次呈阳性,而粪便中寄生虫卵检查为阴性。为排除患者症状的其他可能原因,进行了广泛的诊断程序。两名患者均对驱虫治疗(阿苯达唑 400mg 和甲苯达唑 100mg,每日 2 次,共 3 天)反应良好。本报告强调了在奥地利,对于出现嗜酸性粒细胞增多和肺部症状的患者,也应考虑寄生虫感染的重要性。