Medical Oncology, Hospital Universitario Puerta de Hierro, Madrid, Spain.
Med Oncol. 2011 Dec;28 Suppl 1:S644-6. doi: 10.1007/s12032-010-9687-9. Epub 2010 Oct 7.
Desmoplastic small round cell tumor (DSRCT) is a rare and aggressive cancer that typically arises in teenage boys. As a result of its low prevalence, there have been few studies of its treatment and impact on survival. Here, we report the case of a patient who was refractory to multiple drugs but remains stable with trabectedin. To our knowledge, this is the first published report that supports antitumoral activity of trabectedin in DSRCT.
促纤维增生性小圆细胞肿瘤(DSRCT)是一种罕见且侵袭性强的癌症,通常发生在青少年男性中。由于其发病率低,对其治疗和生存影响的研究很少。在这里,我们报告了一例对多种药物耐药但仍用曲贝替定稳定的患者。据我们所知,这是第一份支持曲贝替定在 DSRCT 中具有抗肿瘤活性的发表报告。