Franchi M, Scorbati E
Clinica Ostetrico-Ginecologica dell'Università di Pavia.
Ann Ostet Ginecol Med Perinat. 1990 Sep-Oct;111(5):296-320.
The Authors review, on the basis of their experience, the literature data concerning chemo-antibiotic prophylaxis in gynaecological surgery. Prophylaxis is widely employed although some important aspects are still under evaluation: bacterial selection and resistance, benefit in case of abdominal hysterectomy or elective Cesarean section, risk of pseudomembranous colitis. The most effective drugs are Piperacillin/Mezlocillin given in a single dose preoperatively. The same drugs are useful in the treatment of postsurgical infections.
作者根据自身经验回顾了有关妇科手术中化学抗生素预防的文献资料。预防措施被广泛应用，尽管一些重要方面仍在评估之中：细菌的选择与耐药性、腹式子宫切除术或择期剖宫产时的益处、假膜性结肠炎的风险。最有效的药物是哌拉西林/美洛西林，于术前单次给药。同样的药物对术后感染的治疗也有效。
