Center of Biomedical Engineering, Frankfurt/M, Germany.
Acad Radiol. 2010 Dec;17(12):1486-91. doi: 10.1016/j.acra.2010.08.010. Epub 2010 Oct 6.
To perform magnetic resonance imaging (MRI) scans regarding material parameter and model validation in computational simulations of mechanical interaction of human soft-tissue with body-supporting devices, enhanced medical prognosis in pressure sore prophylaxis, and comfort optimization in automotive and aircraft seating.
In vivo human gluteal fat and passive muscle tissue material parameters of a volunteer evaluated via combined MRI numerical method and body-supporting foam material parameters employed in finite element (FE) simulations of tissue-support interaction were verified by a defined loading scenario using MRI. MRI of the loaded configurations were performed and compared with simulation results for displacement field information.
Deformation of gluteal skin/fat and passive muscle-tissue and support material under interacting loading using numerical simulation complied with the MRI results. Accordance was found for deformed skin surface and internal fat-muscle tissue boundaries by superimposing experimental and numerical outputs. Further evidence of established through in vivo gluteal tissue parameters was thus provided and tissue material isotropy assumption was shown for use in simulated buttock loading interactions. Additionally, a new concept of FE model validation regarding non-MRI-sensitive materials such as polyurethane foam was introduced comprising peripheral surface visualization.
Imaging techniques are essential in biomechanical modeling and provide key information regarding model validation and validity assessment.
在人体软组织与支撑设备力学相互作用的计算模拟中，进行磁共振成像（MRI）扫描，以验证材料参数和模型，从而提高压疮预防的医学预后，并优化汽车和飞机座椅的舒适度。
志愿者的臀部脂肪和被动肌肉组织的体内材料参数通过联合 MRI 数值方法进行评估，并通过 MRI 对定义的加载情况进行验证，使用有限元（FE）模拟组织支撑相互作用中的泡沫支撑材料参数。对加载状态下的 MRI 进行成像，并对位移场信息的模拟结果进行比较。
使用数值模拟，在相互作用的加载下，臀部皮肤/脂肪和被动肌肉组织以及支撑材料的变形与 MRI 结果一致。通过叠加实验和数值输出，发现了变形的皮肤表面和内部脂肪-肌肉组织边界的一致性。因此，为体内臀部组织参数的建立提供了进一步的证据，并证明可以在模拟臀部加载相互作用中使用组织各向同性假设。此外，还引入了一种新的概念，即针对如聚氨酯泡沫等非 MRI 敏感材料的 FE 模型验证，包括周边表面可视化。
成像技术在生物力学建模中至关重要，为模型验证和有效性评估提供了关键信息。
