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[拉姆齐·亨特综合征。阿昔洛韦治疗的效果(初步研究)]

[Ramsay Hunt syndrome. Effects of the treatment with acyclovir (preliminary study)].

作者信息

Ramos Macías A, Gómez González J L, de Miguel Martínez M I, López Alburquerque T, Lavilla Martín M J, Ruiz Martín F

机构信息

Servicio de ORL, Hospital Clínico, Facultad de Medicina, Universidad de Salamanca.

出版信息

Acta Otorrinolaringol Esp. 1990 Nov-Dec;41(6):387-91.

PMID:2092730
Abstract

Herpes zoster oticus has a poor prognosis with permanent facial nerve dysfunction. We have studied 11 patients in a total group of 131 facial palsies seen in our service for a 20 month period. Four patients had no treatment. Two were treated with prednisone, and five were infused with acyclovir (10 mg/kg every 8 hours over a 10 day hospitalization period) and prednisone. These treatments were observed for 3 to 6 months. Patients follow up was, acyclovir group, 2 patients have achieved a House grade I, 1 patient grade II, 1 patient grade III and 1 left this treatment because side effects was observed. The other patients, 1 have achieved grade I, 2 patients grade II, 2 patients grade III and 1 patient grade V. The differences and final results are discussed.

摘要

耳带状疱疹预后较差,常伴有永久性面神经功能障碍。在我们科室20个月内诊治的131例面瘫患者中,我们研究了其中11例。4例患者未接受治疗。2例接受泼尼松治疗,5例接受阿昔洛韦(住院10天期间每8小时静脉滴注10mg/kg)和泼尼松治疗。对这些治疗进行了3至6个月的观察。阿昔洛韦组患者随访结果为,2例达到House I级,1例II级,1例III级,1例因观察到副作用而退出治疗。其他患者中,1例达到I级,2例II级,2例III级,1例V级。对差异和最终结果进行了讨论。

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Acta Otorrinolaringol Esp. 1990 Nov-Dec;41(6):387-91.
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