Analytical Technology Team, LG Display, Gumi, Korea.
Chirality. 2011 Apr;23(4):281-6. doi: 10.1002/chir.20910. Epub 2010 Oct 6.
(R)-N-3,5-dinitrobenzoyl (DNB) leucine derived chiral selector was used as an HPLC chiral stationary phase for the resolution of various racemic amino acids derivatives. In this study, determination of optical purity of an amino acid derivative was performed by chiral high performance liquid chromatography and 1H and 13C NMR spectroscopy by using the DNB leucine derived chiral selector. The accuracy and precision of each optical purity value are calculated and the data are compared to each other.
(R)-N-3,5-二硝基苯甲酰（DNB）亮氨酸衍生手性选择剂被用作 HPLC 手性固定相，用于拆分各种外消旋氨基酸衍生物。在这项研究中，使用 DNB 亮氨酸衍生手性选择剂通过手性高效液相色谱法和 1H 和 13C NMR 光谱法测定氨基酸衍生物的光学纯度。计算每个光学纯度值的准确性和精密度，并将数据相互比较。
