Furková K, Kaiserová E, Páleníková O, Hruskovic I, Slugen I, Arpasová D, Janota S, Nyulassy S
Detská klinika NsP Akademika L. Dérera, Bratislava.
Cesk Pediatr. 1990 Oct;45(10):591-5.
The authors treated eight children with corticoid dependent syndrome caused by minor abnormalities of the glomeruli with Cyclosporin A. They administered Cyclosporin, 5 mg/kg/24 h., for a period of 8-16 weeks. In three patients they used Cyclosporin A alone, 5 children were given in addition 10 mg Prednisone per day. They achieved complete remission in all patients. During treatment they monitored haematological and biochemical parameters as well as Cyclosporin A levels; before treatment and after its termination they examined also immunological indicators. They did not observe any serious side effects of treatment.
作者用环孢素A治疗了8名因肾小球轻度异常引起的皮质激素依赖综合征患儿。他们给予环孢素5毫克/千克/24小时，持续8 - 16周。3名患者单独使用环孢素A，另外5名儿童每天加用10毫克泼尼松。所有患者均实现完全缓解。治疗期间，他们监测了血液学和生化参数以及环孢素A水平；治疗前和治疗结束后，他们还检查了免疫指标。他们未观察到治疗有任何严重副作用。
