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男性乳房发育症:发展中国家的管理

Gynaecomastia: management in a developing country.

作者信息

Muneer Ambreen, Laghari Zameer Hussain, Shaikh Abdul Razaque, Laghari Qamber Ali

机构信息

Department of Surgery, Liaquat University of Medical and Health Sciences, Jamshoro, Pakistan.

出版信息

J Ayub Med Coll Abbottabad. 2009 Jul-Sep;21(3):7-11.

Abstract

BACKGROUND

Gynaecomastia is a benign enlargement of male breast. It is common in the general population, resulting from various pathophysiological mechanisms. The aim of this study was to describe the presentation and outcome of treatment for gynaecomastia at a University Hospital in Pakistan.

METHODS

A three year retrospective study was carried out of one hundred men with gynaecomastia. Patients were evaluated in detail clinically and by appropriate investigations. They were counselled and kept on hormonal therapy for three months. Surgery was considered for patients with long standing gynaecomastia, failed medical therapy and for cosmetic reasons. Post operative complications and patient's satisfaction was assessed.

RESULTS

Most (90%) cases were idiopathic. Other causes were liver cirrhosis in 4 cases, testicular tumour in two, thyrotoxicosis in one and drug induced (use of cimetidine and Kushta) in two. Carcinoma of the breast was diagnosed in one patient. Most of the patients had bilateral, non tender lump in the breast. Three cases of idiopathic gynaecomastia resolved on danazol. Eighty-eight cases underwent surgical treatment. The mean age of patients who underwent surgery (n = 88) was 30.5 +/- 9.59 years. Most of the patients belonged to 21-30 years age group. Major indications for surgery were failure of medical treatment (45.5%) and cosmetic reasons (34.0%). Mean operating time for subcutaneous mastectomy was 42.2 +/- 3.70 (36-48) minutes. Mean hospital stay after subcutaneous mastectomy was 5.2 +/- 2.44 (2-10) days. The only postoperative complication noted was wound infection (24%). Seventy-two (81.8%) were satisfied with the results of their surgical treatment.

CONCLUSION

Gynaecomastia is the common condition affecting male breasts and most common cause of gynaecomastia is idiopathic. Secondary gynaecomastia may regress in size by treating the primary cause. Idiopathic gynaecomastia do not respond to danazol so they needed surgical treatment. Subcutaneous mastectomy through a periareolar skin incision is a valid procedure for treatment for gynaecomastia and provides satisfactory cosmetic results.

摘要

背景

男性乳房肥大是男性乳腺的良性增大。在普通人群中很常见,由多种病理生理机制引起。本研究的目的是描述巴基斯坦一家大学医院男性乳房肥大的临床表现及治疗结果。

方法

对100例男性乳房肥大患者进行了为期三年的回顾性研究。对患者进行了详细的临床评估和适当的检查。为他们提供了咨询,并给予三个月的激素治疗。对于长期存在男性乳房肥大、药物治疗无效以及出于美容原因的患者,考虑进行手术。评估术后并发症和患者满意度。

结果

大多数(90%)病例为特发性。其他原因包括4例肝硬化、2例睾丸肿瘤、1例甲状腺毒症以及2例药物诱发(使用西咪替丁和库什塔)。1例患者被诊断为乳腺癌。大多数患者乳房有双侧、无压痛肿块。3例特发性男性乳房肥大患者使用达那唑后症状缓解。88例患者接受了手术治疗。接受手术的患者(n = 88)平均年龄为30.5 +/- 9.59岁。大多数患者属于21 - 30岁年龄组。手术的主要指征是药物治疗失败(45.5%)和美容原因(34.0%)。皮下乳房切除术的平均手术时间为42.2 +/- 3.70(36 - 48)分钟。皮下乳房切除术后的平均住院时间为5.2 +/- 2.44(2 - 10)天。唯一记录到的术后并发症是伤口感染(24%)。72例(81.8%)对手术治疗结果满意。

结论

男性乳房肥大是影响男性乳房的常见病症,男性乳房肥大最常见的原因是特发性的。继发性男性乳房肥大通过治疗原发性病因可能会缩小。特发性男性乳房肥大对达那唑无反应,因此需要手术治疗。经乳晕周围皮肤切口进行皮下乳房切除术是治疗男性乳房肥大的有效方法,且美容效果令人满意。

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