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伊拉克和阿富汗服役士兵中新发哮喘。

New-onset asthma among soldiers serving in Iraq and Afghanistan.

机构信息

Veterans Affairs Medical Center, Northport, New York 11768, USA.

出版信息

Allergy Asthma Proc. 2010 Sep-Oct;31(5):67-71. doi: 10.2500/aap.2010.31.3383.

DOI:10.2500/aap.2010.31.3383
PMID:20929596
Abstract

Since June 4, 2004, asthma diagnosed and symptomatic after the age of 12 years has been an exclusion criterion for military enlistment unless exempted via medical waiver. The Department of Defense determined that 13% of U.S. Army Medic visits in Iraq are for new-onset acute respiratory illness; case reports of veterans with asthma that began in Iraq and Afghanistan War zones have surfaced. This prompted our study to determine whether new asthma is diagnosed more frequently among Iraq/Afghanistan War troops versus stateside-based troops. Retrospective review of asthma diagnoses among computerized charts for military personnel discharged from active duty and examined between March 1, 2004 and May 1, 2007, at the Veterans Affairs Medical Center (VAMC), Northport, NY, classified soldiers by (1) deployment status-whether they were stationed in Iraq/Afghanistan for a 1-year tour of duty or stationed in the United States, and (2) VA diagnosis of asthma per International Classification of Disease codes. Associations between deployment and asthma statuses were evaluated/stratified by gender/age group. Eligibility criteria entailed (1) residence in Long Island, (2) aged 18-45 years, and (3) both U.S. military service and discharge dates between March 1, 2004 and May 1, 2007. Out of 6233 patients who served between 2004 and 2007 and were followed at the Northport VAMC, 290 new-onset/prevalent asthma cases were identified. Deployment to Iraq was associated with a significantly higher risk of asthma compared with stateside soldiers (6.6% versus 4.3%; with a crude odds ratio, 1.58; 95% CI, 1.18, 2.11). These associations persist when stratified by gender and age group. Deployment to Iraq and Afghanistan is associated with new-onset asthma. Etiologic studies, surveillance, incidence, epidemiology, and assessing response to therapy are recommended.

摘要

自 2004 年 6 月 4 日起,12 岁以后被诊断为哮喘且有症状的患者被排除在入伍标准之外,除非通过医疗豁免。美国国防部确定,在伊拉克,美国陆军医务人员的 13%就诊是为了治疗新出现的急性呼吸道疾病;有报道称,在伊拉克和阿富汗战区开始出现患有哮喘的退伍军人。这促使我们进行了这项研究,以确定在伊拉克/阿富汗战区服役的新兵中,新诊断出哮喘的比例是否高于美国本土服役的新兵。对 2004 年 3 月 1 日至 2007 年 5 月 1 日期间在纽约州北港退伍军人事务医疗中心(VAMC)退伍的现役军人的哮喘诊断进行了回顾性审查,根据(1)部署状态,即他们是否在伊拉克/阿富汗执行为期 1 年的任务,或驻扎在美国,以及(2)根据国际疾病分类代码对退伍军人事务部诊断的哮喘进行分类。通过性别/年龄组评估/分层了部署与哮喘状态之间的关系。入选标准包括:(1)居住在长岛;(2)年龄在 18-45 岁之间;(3)美国军队服役和退伍日期均在 2004 年 3 月 1 日至 2007 年 5 月 1 日之间。在 2004 年至 2007 年期间服役并在北港退伍军人事务医疗中心接受随访的 6233 名患者中,确定了 290 例新发/现患哮喘病例。与驻扎在美国的士兵相比,部署到伊拉克与哮喘的风险显著增加(6.6%比 4.3%;粗比值比,1.58;95%置信区间,1.18,2.11)。当按性别和年龄组分层时,这些关联仍然存在。部署到伊拉克和阿富汗与新出现的哮喘有关。建议进行病因学研究、监测、发病率、流行病学研究,并评估治疗反应。

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