MacIntyre W J
Department of Nuclear Medicine, Cleveland Clinic Foundation, Ohio 44195-5074.
Eur Heart J. 1990 Dec;11 Suppl I:133-40. doi: 10.1093/eurheartj/11.suppl_i.133.
Developments of various imaging modalities in recent years have resulted in imaging systems with greater spatial resolution, faster data acquisition, and more powerful computer processing. It is the purpose of this report to examine three of these systems, positron emission tomography (PET), magnetic resonance imaging (MRI) and ultrafast computed tomography (cine-CT) with respect to their applicability for determination of cardiac volumes and other characteristics related to hypertension. While each of these modalities has widespread applications and specific advantages, this report will be primarily concerned with two objectives: functional ability to record indicator dilution curves suitable for quantification of flow and the anatomic or geometric ability to measure chamber dimensions with high accuracy. Time concentration curves have been outlined on all modalities and used for quantification of myocardial perfusion and myocardial reserve. Only one modality, cine-CT, determined cardiac output by dilution curves although in vivo arterial recording from PET has demonstrated suitable curves for this application. Both MRI and cine-CT have demonstrated accurate determination of chamber volumes by the geometric method, the latter giving somewhat higher spatial resolution. The advantages of these machines for such purposes have yet to be determined.
近年来，各种成像方式的发展催生了具有更高空间分辨率、更快数据采集速度和更强大计算机处理能力的成像系统。本报告旨在研究其中三种系统，即正电子发射断层扫描（PET）、磁共振成像（MRI）和超快速计算机断层扫描（电影CT），考察它们在测定心脏容积及其他与高血压相关特征方面的适用性。虽然这些成像方式各自都有广泛应用和特定优势，但本报告将主要关注两个目标：记录适合流量定量分析的指示剂稀释曲线的功能能力，以及高精度测量腔室尺寸的解剖学或几何学能力。所有成像方式都已勾勒出时间浓度曲线，并用于心肌灌注和心肌储备的定量分析。尽管PET的体内动脉记录已证明可获得适用于此应用的曲线，但只有电影CT通过稀释曲线测定心输出量。MRI和电影CT都已通过几何学方法准确测定腔室容积，后者的空间分辨率略高。这些仪器用于此类目的的优势尚未确定。
