Maffuz Antonio, Quijano Félix, López Daniel, Hernández-Ramírez Daniel
División de Cirurgía, Departamento de Ginecología Oncológica, Hospital de Oncología, Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, DF México.
Ginecol Obstet Mex. 2010 Jul;78(7):345-51.
in patients with early-stage cervical cancer (FIGO IA, IB2 and IIA), the incidence of lymph node metastases is up to 15%; the majority of early cervical cancer patients with pelvic and para-aortic lymphadenectomy does not benefit with the procedure and are at risk of associated morbidity (linfocyst, lymphedema, vascular or nerve damage).
To describe the experience and usefulness of lymphatic mapping and sentinel lymph node with total laparoscopic radical hysterectomy in early stage cervical cancer.
Retrospective study in patients with diagnosis of cervical cancer in early stage, submitted to laparoscopic radical hysterectomy with lymphatic mapping and sentinel lymph node biopsy. We analyzed sentinel lymph node identification, false negative rate and surgical variables.
in 36 months 15 patients were included, two in IA2 FIGO stage, twelve IB1 and one IIA; thirteen patients were mapping with combined technique and two only with dye. The sentinel lymph node identification rate was 87% (two failures in the patients using only blue dye); the false negative rate was 0%.
Laparoscopic radical hysterectomy with lymphatic mapping is a secure technique for patients with early stage cervical cancer; it allows the correct identification of lymph node status as the principal prognostic factor. We recommend the use of combined technique (radiocolloid tracer and blue dye) for best rate sentinel lymph node identification.
在早期宫颈癌(国际妇产科联盟[FIGO]IA期、IB2期和IIA期)患者中,淋巴结转移发生率高达15%;大多数接受盆腔及腹主动脉旁淋巴结切除术的早期宫颈癌患者并未从该手术中获益,且存在相关并发症(淋巴囊肿、淋巴水肿、血管或神经损伤)的风险。
描述在早期宫颈癌患者中,采用全腹腔镜根治性子宫切除术联合淋巴绘图及前哨淋巴结活检的经验及效用。
对诊断为早期宫颈癌并接受腹腔镜根治性子宫切除术联合淋巴绘图及前哨淋巴结活检的患者进行回顾性研究。我们分析了前哨淋巴结的识别情况、假阴性率及手术变量。
在36个月内纳入15例患者,其中FIGO IA2期2例,IB1期12例,IIA期1例;13例患者采用联合技术进行绘图,2例仅使用染料。前哨淋巴结识别率为87%(仅使用蓝色染料的患者中有2例失败);假阴性率为0%。
对于早期宫颈癌患者,腹腔镜根治性子宫切除术联合淋巴绘图是一种安全的技术;它能够正确识别作为主要预后因素的淋巴结状态。我们推荐使用联合技术(放射性胶体示踪剂和蓝色染料)以获得最佳的前哨淋巴结识别率。