Du Jiang, Li Yaling, Wang Qing, Batchu Nasra, Zou Junkai, Sun Chao, Lv Shulan, Song Qing, Li Qiling
Department of Obstetrics and Gynecology, First Affiliated Hospital, Xi'an Jiaotong University, Xi'an, Shaanxi 710061, P.R. China.
Gongzhuling Health Workers High School, Gongzhuling, Jilin 136100, P.R. China.
Oncol Lett. 2017 Dec;14(6):7669-7675. doi: 10.3892/ol.2017.7219. Epub 2017 Oct 18.
The intraoperative mapping of sentinel lymph nodes (SLNs) is part of the treatment strategy for a number of types of tumor. To retrospectively compare results from the mapping of pelvic SLNs for gynecological oncology, using distinct dyes, the present review was conducted to determine the clinical significance of SLN mapping for gynecological oncology. In addition, the present study aimed at identifying an improved choice for SLN mapping tracers in clinical application. Each dye exhibits demerits when applied in the clinical environment. The combination of radioisotopes and blue dyes was identified to exhibit the most accurate detection rate of SLN drainage of gynecological oncology. However, contrast agents were unable to identify whether a SLN is positive or negative for metastasis prior to pathologic examination; additional studies are required.
前哨淋巴结（SLN）的术中定位是多种肿瘤治疗策略的一部分。为了回顾性比较使用不同染料对妇科肿瘤盆腔SLN进行定位的结果，本综述旨在确定SLN定位对妇科肿瘤的临床意义。此外，本研究旨在确定临床应用中SLN定位示踪剂的更佳选择。每种染料在临床应用中都有缺点。放射性同位素和蓝色染料的组合被认为对妇科肿瘤SLN引流的检测率最准确。然而，在病理检查之前，造影剂无法确定SLN是否发生转移；还需要进一步研究。
