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[紫桑根皮的化学成分]

[Chemical constituents from root barks of Morus atropurpurea].

作者信息

Wu Dongling, Zhang Xiaoqi, Huang Xiaojun, He Xuemei, Wang Guocai, Ye Wencai

机构信息

Department of Phytochemistry, China Pharmaceutical University, Nanjing 210009, China.

出版信息

Zhongguo Zhong Yao Za Zhi. 2010 Aug;35(15):1978-82. doi: 10.4268/cjcmm20101514.

DOI:10.4268/cjcmm20101514
PMID:20931850
Abstract

OBJECTIVE

To study the chemical constituents from the root barks of Morus atropurpurea.

METHOD

The chemical constituents from the 70% ethanol extract of M. atropurpurea were isolated and purified by column chromatographic methods. Their structures were identified by physico-chemical properties as well as spectral data.

RESULT

Fifteen compounds were isolated and identified as sanggenol O(1), kuwanon S(2), moracin C(3), mulberrofuran A(4), mulberrofuran B(5), mulberrofuran C(6), mulberrofuran G(7), mulberroside A(8), mulberroside C(9), 1-deoxynojirimycin(10), 2-O-alpha-D-galactopyranosyl-1-deoxynojirimycin(11), fagomine(12), betulinic acid(13), ursolic acid(14) and beta-sitosterol(15).

CONCLUSION

Compounds 1-6 and 8-13 were isolated from M. atropurpurea for the first time.

摘要

目的

研究紫桑根皮的化学成分。

方法

采用柱色谱法对紫桑70%乙醇提取物中的化学成分进行分离纯化,并通过理化性质和光谱数据鉴定其结构。

结果

分离鉴定出15个化合物,分别为桑根醇O(1)、库湾诺酮S(2)、桑色素C(3)、桑呋喃A(4)、桑呋喃B(5)、桑呋喃C(6)、桑呋喃G(7)、桑木苷A(8)、桑木苷C(9)、1-脱氧野尻霉素(10)、2-O-α-D-吡喃半乳糖基-1-脱氧野尻霉素(11)、法戈明(12)、桦木酸(13)、熊果酸(14)和β-谷甾醇(15)。

结论

化合物1 - 6、8 - 13首次从紫桑中分离得到。

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