Department of Chemical and Biological Engineering, Chalmers University of Technology, SE-412 96 Göteborg, Sweden.
Langmuir. 2010 Nov 16;26(22):16630-3. doi: 10.1021/la102719w. Epub 2010 Oct 8.
Lipid bilayer formation via vesicle fusion on mesoporous silica and mesoporous titania was investigated using quartz crystal microbalance with dissipation monitoring (QCM-D) and fluorescent recovery after photobleaching (FRAP). Results showed that lipid bilayers were formed on mesoporous silica and that intact vesicle adsorption was obtained on mesoporous titania. From the FRAP results, it could be concluded that the lipid bilayer was fluid; however, it had a smaller diffusivity constant compared to bilayers supported on a nonporous silica.
采用石英晶体微天平耗散监测（QCM-D）和光漂白荧光恢复（FRAP）技术研究了脂质体在介孔二氧化硅和介孔二氧化钛上通过囊泡融合形成脂质双层的过程。结果表明，脂质双层可在介孔二氧化硅上形成，而完整的囊泡吸附可在介孔二氧化钛上获得。从 FRAP 结果可以得出结论，脂质双层是流体的；然而，与非多孔二氧化硅支撑的双层相比，其扩散常数较小。
