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Colorectal cancer: cetuximab, KRAS, BRAF, PIK3CA mutations and beyond.

作者信息

Katsios Christos, Ziogas Dimosthenis E, Roukos Dimitrios H

出版信息

Expert Rev Gastroenterol Hepatol. 2010 Oct;4(5):525-9. doi: 10.1586/egh.10.62.

DOI:10.1586/egh.10.62
PMID:20932136
Abstract
摘要

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Colorectal cancer: cetuximab, KRAS, BRAF, PIK3CA mutations and beyond.结直肠癌:西妥昔单抗、KRAS、BRAF、PIK3CA突变及其他相关研究
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[Gene mutation (KRAS, BRAF, PIK3CA) and clinical benefit of anti-EGFR antibody].[基因变异(KRAS、BRAF、PIK3CA)与抗表皮生长因子受体抗体的临床获益]
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Predicting cetuximab accumulation in KRAS wild-type and KRAS mutant colorectal cancer using 64Cu-labeled cetuximab positron emission tomography.使用 64Cu 标记的西妥昔单抗正电子发射断层扫描预测 KRAS 野生型和 KRAS 突变型结直肠癌中的西妥昔单抗蓄积。
Cancer Sci. 2012 Mar;103(3):600-5. doi: 10.1111/j.1349-7006.2011.02166.x. Epub 2011 Dec 23.
2
Laparoscopic low anterior resection with total mesorectal excision for rectal cancer.腹腔镜低位前切除术联合全直肠系膜切除术治疗直肠癌。
Surg Endosc. 2012 Feb;26(2):578-9. doi: 10.1007/s00464-011-1893-9.
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Single-incision laparoscopic surgery for colorectal cancer.
结直肠癌的单孔腹腔镜手术
Surg Endosc. 2011 Aug;25(8):2764-5. doi: 10.1007/s00464-011-1621-5.
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Linking epidermal growth factor plasma levels with the prognosis and treatment response of colorectal cancer patients treated with a minimally invasive approach: does it have clinical utility?将表皮生长因子血浆水平与接受微创治疗的结直肠癌患者的预后和治疗反应相关联:它具有临床实用性吗?
Surg Endosc. 2011 Aug;25(8):2766-7; author reply 2768. doi: 10.1007/s00464-011-1622-4.
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Optimizing preoperative management of rectal cancer.优化直肠癌的术前管理。
World J Surg. 2011 Jun;35(6):1416-7; author reply 1418-9. doi: 10.1007/s00268-010-0930-5.
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Histological and immediate postoperative outcome after preoperative cetuximab: case-matched control study.术前使用西妥昔单抗后的组织学及术后即时结果:病例匹配对照研究
World J Surg. 2011 May;35(5):1153-4. doi: 10.1007/s00268-010-0915-4.
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Clinicopathologic characteristics of colorectal cancer patients with synchronous and metachronous gastric cancer.
World J Surg. 2011 Mar;35(3):700-1. doi: 10.1007/s00268-010-0868-7.
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Nonepithelial, submucosal gastric tumors: is laparoscopic wedge resection the optimal treatment?非上皮性胃黏膜下肿瘤:腹腔镜楔形切除术是最佳治疗方法吗?
Surg Endosc. 2011 Jun;25(6):2052-3; author reply 2054. doi: 10.1007/s00464-010-1447-6.
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Exploring indications for laparoscopic primary tumor resection in metastatic colorectal cancer.
Surg Endosc. 2011 May;25(5):1706-7. doi: 10.1007/s00464-010-1446-7.
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Simultaneous resection of primary colorectal cancer and synchronous liver metastases.同时切除原发性结直肠癌和同步性肝转移瘤。
World J Surg. 2011 Apr;35(4):926-7; author reply 928. doi: 10.1007/s00268-010-0833-5.