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针对所有经跨大西洋协作组分级的股腘动脉病变进行血管内治疗的成功率。

The success of endovascular therapy for all TransAtlantic Society Consensus graded femoropopliteal lesions.

作者信息

Han Daniel K, Shah Tejas R, Ellozy Sharif H, Vouyouka Ageliki G, Marin Michael L, Faries Peter L

机构信息

Department of Surgery, Mount Sinai School of Medicine, New York, NY, USA.

出版信息

Ann Vasc Surg. 2011 Jan;25(1):15-24. doi: 10.1016/j.avsg.2010.06.003. Epub 2010 Oct 8.

Abstract

BACKGROUND

Advances in technology and practice have led to increased endovascular management of all TransAtlantic Society Consensus (TASC)-graded lesions. This study aims to evaluate the success of endovascular therapy in the management of TASC-graded femoropopliteal lesions.

METHODS

Patients undergoing endovascular treatment for femoropopliteal lesions between July 1999 and August 2008 were divided by TASC scores and evaluated for primary, assisted-primary, and secondary patency rates at 12 and 24 months. Secondary endpoints included limb loss and postoperative complications.

RESULTS

A total of 499 femoropopliteal lesions in 427 patients were treated with endovascular interventions. Score distribution for TASC type A, type B, type C, and type D lesions was 26 (5.2%), 140 (28.1%), 168 (33.7%), and 165 (33.1%), respectively. Primary, assisted-primary, and secondary patency rates at 24 months were 77.7 ± 3.2%, 78.9 ± 3.2%, and 86.7 ± 2.6%, respectively, for TASC type A + B lesions, 76.0 ± 3.3%, 77.2 ± 3.2%, and 85.0 ± 2.8%, respectively, for TASC type C lesions, and 61.2 ± 3.8%, 61.2 ± 3.8%, and 78.2 ± 3.2%, respectively, for TASC type D lesions. Compared with TASC type A + B and TASC type C lesions, TASC type D lesions were associated with worse primary and assisted-primary patency rates. However, there was no statistically significant difference in secondary patency between TASC type A + B and TASC type D lesions. The TASC score was not a significant predictor of postoperative complication rates. The 24-month limb salvage rate in patients with TASC type D lesions presenting with critical limb ischemia was 71.9 ± 8.0%.

CONCLUSION

It was observed that all femoropopliteal lesions can be safely and effectively managed with endovascular therapy. Although TASC type D lesions do have lower primary and assisted-primary patency rates, high secondary patency rates comparable with other TASC scores can be achieved with effective prevention of limb loss. These data provide evidence to support endovascular therapy as primary management for all femoropopliteal lesions regardless of the TASC score.

摘要

背景

技术和实践的进步使得所有经跨大西洋协作组(TASC)分级的病变的血管内治疗有所增加。本研究旨在评估血管内治疗在TASC分级的股腘动脉病变管理中的成功率。

方法

将1999年7月至2008年8月期间接受股腘动脉病变血管内治疗的患者按TASC评分进行分组,并评估其在12个月和24个月时的一期通畅率、辅助一期通畅率和二期通畅率。次要终点包括肢体丢失和术后并发症。

结果

427例患者共499处股腘动脉病变接受了血管内介入治疗。TASC A、B、C、D型病变的评分分布分别为26处(5.2%)、140处(28.1%)、168处(33.7%)和165处(33.1%)。TASC A + B型病变24个月时的一期通畅率、辅助一期通畅率和二期通畅率分别为77.7 ± 3.2%、78.9 ± 3.2%和86.7 ± 2.6%,TASC C型病变分别为76.0 ± 3.3%、77.2 ± 3.2%和85.0 ± 2.8%,TASC D型病变分别为61.2 ± 3.8%、61.2 ± 3.8%和78.2 ± 3.2%。与TASC A + B型和TASC C型病变相比,TASC D型病变的一期和辅助一期通畅率较差。然而,TASC A + B型和TASC D型病变在二期通畅率方面无统计学显著差异。TASC评分不是术后并发症发生率的显著预测因素。出现严重肢体缺血的TASC D型病变患者24个月时的肢体挽救率为71.9 ± 8.0%。

结论

观察到所有股腘动脉病变均可通过血管内治疗安全有效地进行管理。虽然TASC D型病变的一期和辅助一期通畅率较低,但通过有效预防肢体丢失可实现与其他TASC评分相当的高二期通畅率。这些数据为支持血管内治疗作为所有股腘动脉病变的主要治疗方法提供了证据,无论其TASC评分如何。

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