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股腘段TASC C-D级病变血管内治疗的临床随访

Clinical follow-up in endovascular treatment for TASC C-D lesions in femoro-popliteal segment.

作者信息

Rabellino Martin, Zander Tobias, Baldi Sebastian, Garcia Nielsen Luis, Aragon-Sanchez F Javier, Zerolo Ignacio, Llorens Rafael, Maynar Manuel

机构信息

Endoluminal Diagnostic and Therapeutic Service, HOSPITEN Group, Tenerife, Spain.

出版信息

Catheter Cardiovasc Interv. 2009 Apr 1;73(5):701-5. doi: 10.1002/ccd.21971.

Abstract

OBJECTIVE

To demonstrate the technical success and clinical follow-up after endovascular treatment of femoropopliteal segment TASC II C and D lesions.

METHODS

From July 2002 to February 2007, 234 limbs in 190 patients with femoropopliteal segment TASC II C (n = 112) and D (n = 122) lesions were treated. Endovascular treatment consisted of PTA, fibrinolysis and PTA, subintimal recanalization and PTA, and finally stent graft. Patients were clinically evaluated at 30 days, 3, 6 month, and at 1 year in the outpatient setting with clinical examination and ankle-brachial indices (ABI). In the case of stent placement, additional ultrasound evaluation was performed at 12, 24, and 48 month.

RESULTS

49.5% of procedures were performed on patients with lifestyle-limiting claudication (IC) and 50.5% were performed for critical limb ischemia (CLI). Technical success, defined as successful recanalization and treatment of the occluded vessel, was achieved in 97% of cases. Periprocedural mortality was 3.15% and all deaths occurred in the CLI group. A follow-up 13 +/- 6 months and was achieved in 76%. During the follow-up, clinical outcome for IC group and clinical CLI group was asymptomatic 72% vs. 29.8%, symptomatic with clinical improvement 22% vs. 33.7%, and major amputation 3% vs. 23.3%.

CONCLUSION

The majority of claudicating patients with femoropopliteal TASC II C and D lesions will benefit from the endovascular treatment. Patient presenting CLI have a worse outcome, nevertheless the endovascular treatment can delay amputation, preserving the native vessel and does not impede surgical bypass if needed. For this reason, we consider that endovascular treatment may be the first choice treatment even in femoropopliteal TASC II C and D lesions.

摘要

目的

展示股腘段TASC II C型和D型病变血管内治疗后的技术成功率及临床随访情况。

方法

2002年7月至2007年2月,对190例患有股腘段TASC II C型(n = 112)和D型(n = 122)病变的患者的234条肢体进行了治疗。血管内治疗包括经皮腔内血管成形术(PTA)、溶栓与PTA、内膜下再通与PTA,最后进行支架植入。在门诊对患者进行临床评估,于30天、3个月、6个月及1年时进行临床检查和踝肱指数(ABI)测量。若进行了支架置入,在12个月、24个月和48个月时还需额外进行超声评估。

结果

49.5%的手术针对有生活方式受限性间歇性跛行(IC)的患者进行,50.5%的手术针对严重肢体缺血(CLI)患者进行。技术成功率定义为闭塞血管成功再通并得到治疗,97%的病例实现了技术成功。围手术期死亡率为3.15%,所有死亡均发生在CLI组。随访时间为13±6个月,76%的患者完成了随访。随访期间,IC组和临床CLI组的临床结局分别为无症状者占72% vs. 29.8%,症状有临床改善者占22% vs. 33.7%,进行大截肢者占3% vs. 23.3%。

结论

大多数患有股腘段TASC II C型和D型病变的间歇性跛行患者将从血管内治疗中获益。CLI患者的结局较差,不过血管内治疗可延迟截肢,保留自体血管,且如有需要不妨碍手术旁路治疗。因此,我们认为即使对于股腘段TASC II C型和D型病变,血管内治疗也可能是首选治疗方法。

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