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腹腔镜卵巢子宫内膜囊肿切除术:外科医生的经验可能会影响体外受精-胞浆内单精子注射治疗不孕患者的卵巢储备和活产率。

Laparoscopic ovarian cystectomy of endometriomas: surgeons' experience may affect ovarian reserve and live-born rate in infertile patients with in vitro fertilization-intracytoplasmic sperm injection.

机构信息

Department of Obstetrics and Gynecology, Chang Gung Memorial Hospital at Linkou and Chang Gung University College of Medicine, Kwei-Shan, Taoyuan, Taiwan.

出版信息

Eur J Obstet Gynecol Reprod Biol. 2010 Oct;152(2):172-5. doi: 10.1016/j.ejogrb.2010.05.016. Epub 2010 Jun 17.

Abstract

OBJECTIVE

To assess whether the laparoscopist's experience can affect ovarian reserve and pregnancy outcome in vitro fertilization-intracytoplasmic sperm injection (IVF-ICSI) patients who previously underwent laparoscopic conservative treatment for ovarian endometriomas.

STUDY DESIGN

One hundred and forty-nine IVF-ICSI cycles with infertile patients who previously underwent laparoscopic conservative treatment for ovarian endometriomas were enrolled. There were 76 cycles with an inexperienced surgeon and 73 cycles with an experienced surgeon.

RESULTS

The number of antral follicle count (7.5±3.8 vs. 9.6±6.6; p=0.011), and live-born rate per cycle (9.3% vs. 32.9%; p<0.001) were significantly lower in the inexperienced group comparing with the experienced group. However, the mean number of oocytes, fertilization rate, mean number of embryos transferred, rate of good-quality embryos transferred, implantation rate and clinical pregnancy were similar between both groups.

CONCLUSIONS

The experience of the laparoscopist may affect ovarian reserve and live-born rate after treating ovarian endometrioma in infertile women with IVF-ICSI.

摘要

目的

评估腹腔镜医师的经验是否会影响先前接受腹腔镜保守治疗卵巢子宫内膜异位症的体外受精-胞浆内单精子注射(IVF-ICSI)患者的卵巢储备和妊娠结局。

研究设计

共纳入 149 个因不孕而接受先前腹腔镜保守治疗卵巢子宫内膜异位症的 IVF-ICSI 周期。其中 76 个周期由经验不足的外科医生进行,73 个周期由经验丰富的外科医生进行。

结果

与经验丰富组相比,经验不足组的窦卵泡计数(7.5±3.8 对 9.6±6.6;p=0.011)和每周期活产率(9.3%对 32.9%;p<0.001)显著降低。然而,两组之间的平均获卵数、受精率、平均胚胎移植数、优质胚胎移植率、着床率和临床妊娠率相似。

结论

腹腔镜医师的经验可能会影响接受 IVF-ICSI 的不孕妇女治疗卵巢子宫内膜异位症后的卵巢储备和活产率。

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