Department of General Chemistry, University of Pavia, via Taramelli 12, 27100 Pavia, Italy.
J Chromatogr A. 2010 Nov 12;1217(46):7275-81. doi: 10.1016/j.chroma.2010.09.024. Epub 2010 Sep 17.
Presented hereafter is the novel application of differently functionalized multi-walled carbon nanotubes (f-MWCNTs) as stationary phases for the GC separation of C(1)-C(5) alcohols and esters. Low-cost packed columns, easily prepared in laboratory, were used with satisfactory results. Depending on the functional groups introduced on the pristine MWCNTs, remarkably different behaviours have been observed, thus indicating that derivatization is a key factor to achieve optimal resolution. The best performance was shown by the 2,2'-(ethylenedioxy)diethylamine derivatized MWCNTs, allowing the separation of alcohol isomers, for this reason chosen for the investigation of fermentation by-products in distilled spirits. The degree of derivatization has been assessed for each packing material by thermogravimetric analysis (TGA). A computational study has been performed to correlate the physico-chemical properties of alcohol probes with the retention behaviour.
以下介绍了不同功能化多壁碳纳米管（f-MWCNTs）作为 GC 分离 C(1)-C(5)醇和酯的固定相的新应用。使用了实验室中易于制备的低成本填充柱，取得了令人满意的结果。根据在原始 MWCNTs 上引入的官能团，观察到了明显不同的行为，这表明衍生化是实现最佳分辨率的关键因素。2,2'-(乙二氧基)二乙胺衍生化的 MWCNTs 表现出最佳性能，能够分离醇异构体，因此选择其用于研究蒸馏酒中的发酵副产物。通过热重分析（TGA）评估了每种包装材料的衍生化程度。还进行了计算研究，以将醇探针的物理化学性质与保留行为相关联。
