University of Leipzig - Heart Center, Clinic for Cardiac Surgery, Leipzig, Germany.
Eur J Cardiothorac Surg. 2011 May;39(5):657-61. doi: 10.1016/j.ejcts.2010.08.051.
Few studies have focussed on the outcomes of tricuspid valve (TV) repair in patients with a right ventricular permanent pacemaker lead (PPL) and tricuspid regurgitation (TR).
Retrospective analysis of all patients with a PPL undergoing TV repair (annuloplasty ring in 83 patients and De Vega annuloplasty in 33 patients) between April 2001 and May 2008 (n=116) was performed. The mean patient age was 71 ± 8.8 years; 59.8% were female, and the average European System for Cardiac Operative Risk Evaluation (EuroSCORE) was 16.4 ± 14.5%. Follow-up was 100% complete with a mean duration of 19.4 ± 20.3 months.
In addition to annular dilatation, leaflet injury secondary to PPL was observed in eight patients (7%). Isolated ring implantation or De Vega annuloplasty was performed in all patients, including five of the eight patients with leaflet injury. In the remaining three patients, the PPL was removed and an epicardial lead was implanted. A 30-day mortality was 14.6% and a 5-year survival 45% (95% confidence interval (CI): 29.4-61.6%). Four patients underwent TV re-operation resulting in a 5-year freedom of 93.4% from TV-related re-operation (95% CI: 88.2-97.7). Two of the four re-operated patients had PPL-related leaflet injury at the time of the initial operation and the PPL was left in situ.
Patients with a pre-existing PPL, who require TV surgery for significant TR, however without evidence of PPL-induced TR, can undergo TV repair without removal of the PPL. In patients with evidence of PPL-related TR, we suggest PPL removal followed by insertion of an epicardal or transcoronary sinus lead.
鲜有研究关注合并永久性右心室起搏器导线(PPL)和三尖瓣反流(TR)的患者行三尖瓣(TV)修复的结局。
回顾性分析 2001 年 4 月至 2008 年 5 月间所有行 TV 修复术(83 例行瓣环成形环,33 例行 De Vega 瓣环成形术)的 PPL 患者(n=116)。患者平均年龄 71±8.8 岁,59.8%为女性,平均欧洲心脏手术风险评估系统(EuroSCORE)为 16.4±14.5%。随访率 100%,平均随访时间 19.4±20.3 个月。
除环形扩张外,8 例患者(7%)还存在因 PPL 导致的瓣叶损伤。所有患者均行单纯环植入或 De Vega 瓣环成形术,包括 8 例瓣叶损伤患者中的 5 例。其余 3 例患者则移除 PPL 并植入心外膜导线。30 天死亡率为 14.6%,5 年生存率为 45%(95%可信区间(CI):29.4-61.6%)。4 例患者行 TV 再次手术,5 年 TV 相关再手术的无事件率为 93.4%(95%CI:88.2-97.7)。4 例再次手术患者中有 2 例在初次手术时存在 PPL 相关瓣叶损伤,且 PPL 仍保留在位。
对于因重度 TR 而需行 TV 手术但无 PPL 导致 TR 证据的合并预存 PPL 的患者,可不移除 PPL 而行 TV 修复术。对于存在 PPL 相关 TR 证据的患者,我们建议移除 PPL 后,植入心外膜或经冠状窦导线。