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改善血液透析患者的 CKD-MBD 管理:实施更好实践的障碍分析。

Improving CKD-MBD management in haemodialysis patients: barrier analysis for implementing better practice.

机构信息

Department of Nephrology, Monash Medical Centre, Clayton, Victoria, Australia.

出版信息

Nephrol Dial Transplant. 2011 Apr;26(4):1319-26. doi: 10.1093/ndt/gfq602. Epub 2010 Oct 8.

Abstract

BACKGROUND

Although clinical guidelines exist for optimal levels of serum markers of chronic kidney disease mineral and bone disorder (CKD-MBD), target parameters are not achieved in many haemodialysis (HD) patients. The reason for this evidence-practice gap is unclear and more information from patients and healthcare professionals is required to improve knowledge transfer. We aimed to determine potential barriers by surveying HD patients and staff about awareness and management of CKD-MBD.

METHODS

A total of 136 prevalent HD patients, 25 nephrologists and 58 dialysis nurses/technicians were surveyed. Three separate questionnaires included issues of knowledge and awareness of CKD-MBD and factors limiting management (including compliance, medications and general understanding).

RESULTS

Of patients surveyed, 84% had heard of phosphate, but 42% were unsure of high phosphate foods and 46% unaware of consequences of elevated phosphate. Twenty-seven percent and thirty-five percent of patients, respectively, had difficulty taking or forgetting to take phosphate binders. Seventy-four percent of patients wanted to know more about CKD-MBD (40% via written material). Of nephrologists surveyed, 76% thought non-compliance with phosphate binders was the main reason for poor control of phosphate (predominantly related to poor patient understanding); 84% thought patients wanted to know more but only 28% provided written material on CKD-MBD. Of dialysis staff surveyed, 63% thought non-compliance with binders explained poor control, the main reason being lack of patient understanding; 88% thought patients wanted to know more but only 17% provided written education.

CONCLUSIONS

Implementation of an intensive educational programme, with a multi-faceted approach, for HD patients may promote better control of CKD-MBD and improve achievement of target levels.

摘要

背景

尽管存在关于慢性肾脏病矿物质和骨异常(CKD-MBD)血清标志物最佳水平的临床指南,但许多血液透析(HD)患者并未达到目标参数。造成这种证据与实践之间差距的原因尚不清楚,需要更多来自患者和医疗保健专业人员的信息,以改善知识转移。我们旨在通过调查 HD 患者和工作人员对 CKD-MBD 的认识和管理情况,确定潜在的障碍。

方法

共调查了 136 名现患 HD 患者、25 名肾病医生和 58 名透析护士/技师。三个独立的问卷包括 CKD-MBD 的知识和意识问题以及管理限制因素(包括依从性、药物和一般理解)。

结果

在所调查的患者中,84%听说过磷酸盐,但 42%不确定高磷酸盐食物,46%不知道高磷酸盐的后果。分别有 27%和 35%的患者服用或忘记服用磷酸盐结合剂有困难。74%的患者希望更多地了解 CKD-MBD(40%通过书面材料)。在所调查的肾病医生中,76%认为磷酸盐结合剂的不依从是控制磷酸盐不良的主要原因(主要与患者理解能力差有关);84%认为患者希望了解更多信息,但只有 28%提供了 CKD-MBD 的书面材料。在所调查的透析工作人员中,63%认为不依从结合剂可以解释磷酸盐控制不佳,主要原因是患者理解能力不足;88%认为患者希望了解更多信息,但只有 17%提供书面教育。

结论

对 HD 患者实施强化教育计划,采取多方面的方法,可能会促进更好地控制 CKD-MBD,并提高目标水平的达标率。

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