Gang E, Peter T, Ma H
First Affiliated Hospital of Sun-Yat Sen University of Medical Sciences, Guangzhou.
Zhonghua Xin Xue Guan Bing Za Zhi. 1990 Dec;18(6):331-2, 381.
The prevalence of ventricular late potentials (LP) in acute myocardial infarction (AMI) and the relationship between the presence of LP and the occurrence of spontaneous sustained ventricular tachycardia (VT) or fibrillation (VE) in the early phase (within 10 days) of AMI were studied. A total of 251 consecutive patients who had an uninterrupted natural history before special treatment formed this study. Sustained VT or VF occurred in 20 patients (8%). LP were recorded in 67 patients (27%). The incidence of LP was significantly higher among patients with VT/VF than among those without VT/VF (12 of 20, or 60%, vs 55 of 231, or 24%, P less than 0.01). The subgroup of patients whose VT/VF occurred within 1 hour of onset of AMI also showed a higher incidence of LP (5 of 9, or 56%, vs 55 of 231, or 24%, P less than 0.05). The results showed that the mechanism of VT/VF in early period including those happened within 1 hour of onset of AMI in man is due to reentry, and that LP can help to identify those high risk patients with a propensity to develop VT/VF in early period of AMI.
研究了急性心肌梗死(AMI)患者心室晚电位(LP)的发生率,以及LP的存在与AMI早期(10天内)自发性持续性室性心动过速(VT)或心室颤动(VF)发生之间的关系。本研究共纳入251例在接受特殊治疗前具有连续自然病程的患者。20例患者(8%)发生了持续性VT或VF。67例患者(27%)记录到LP。发生VT/VF的患者中LP的发生率显著高于未发生VT/VF的患者(20例中的12例,即60%,对比231例中的55例,即24%,P<0.01)。AMI发病1小时内发生VT/VF的患者亚组中LP的发生率也较高(9例中的5例,即56%,对比231例中的55例,即24%,P<0.05)。结果表明,包括在AMI发病1小时内发生的VT/VF在内,早期VT/VF的机制是折返,并且LP有助于识别那些在AMI早期有发生VT/VF倾向的高危患者。