Laboratory of Animal Physiology, Department of Zoology, School of Biology, Faculty of Science, Aristotle University of Thessaloniki, Thessaloniki 54124, Greece.
Comp Biochem Physiol C Toxicol Pharmacol. 2011 Jan;153(1):133-40. doi: 10.1016/j.cbpc.2010.10.001. Epub 2010 Oct 16.
The present study aims to examine whether the seasonal changes in the levels of heavy metals Cd and Pb in the gills of sublittoral mussel Modiolus barbatus from populations distributed in Thermaikos Gulf are correlated to seasonal molecular (Heat Shock Response) and metabolic stress responses of this species. Our results indicate a season effect in the accumulation of heavy metals in the gills of bivalves in the area of Thermaikos Gulf, possibly implicating biological (reproductive cycle), natural (rivers' flow) and anthropogenic factors. Among the members of heat shock proteins (Hsps) examined, inducible Hsp70 seemed to play a major cytoprotective role against toxicity of metals. However, bivalves' tolerance against heavy metals may decrease during warming, arising further questions for their survival in context of global warming.
本研究旨在探讨 Thermaikos 湾分布的贻贝种群鳃中重金属 Cd 和 Pb 的水平是否随季节变化，以及这种变化是否与该物种的季节性分子（热激反应）和代谢应激反应有关。我们的结果表明，Thermaikos 湾地区双壳类动物鳃中重金属的积累存在季节效应，这可能涉及生物（生殖周期）、自然（河流流量）和人为因素。在所研究的热休克蛋白（Hsps）成员中，诱导型 Hsp70 似乎对金属毒性起着主要的细胞保护作用。然而，随着气候变暖，双壳类动物对重金属的耐受性可能会降低，这对它们在全球变暖背景下的生存提出了更多的问题。
