Division of Neonatology, Department of Pediatrics, School of Medicine, University of Alabama at Birmingham, 9380 Women and Infants Center,1700 6th Ave South Birmingham, AL 35233, USA.
Pediatrics. 2010 Nov;126(5):e1064-71. doi: 10.1542/peds.2009-3464. Epub 2010 Oct 11.
This study was designed to test the hypothesis that 2 training programs would reduce incrementally 7-day neonatal mortality rates for low-risk institutional deliveries.
Using a train-the-trainer model, certified research midwives sequentially trained the midwives who performed deliveries in low-risk, first-level, urban, community health clinics in 2 cities in Zambia in the protocol and data collection, in the World Health Organization Essential Newborn Care (ENC) course (universal precautions and cleanliness, routine neonatal care, resuscitation, thermoregulation, breastfeeding, kangaroo care, care of small infants, and common illnesses), and in the American Academy of Pediatrics Neonatal Resuscitation Program (in-depth basic resuscitation). Data were collected during 3 periods, after implementation of each training course.
A total of 71 689 neonates were enrolled in the 3 study periods. All-cause, 7-day neonatal mortality rates decreased from 11.5 deaths per 1000 live births to 6.8 deaths per 1000 live births after ENC training (relative risk: 0.59 [95% confidence interval: 0.48-0.77]; P < .001), because of decreases in rates of deaths attributable to birth asphyxia and infection. Perinatal mortality rates but not stillbirth rates decreased. The 7-day neonatal mortality rate was decreased further after Neonatal Resuscitation Program training, after correction for loss to follow-up monitoring.
ENC training for midwives reduced 7-day neonatal mortality rates in low-risk clinics. Additional in-depth basic training in neonatal resuscitation may reduce mortality rates further.
本研究旨在检验以下假设,即两种培训方案可逐步降低低危机构分娩的 7 日新生儿死亡率。
利用培训师培训模式,经认证的研究助产士连续培训在赞比亚两个城市的低危一级城市社区卫生诊所进行分娩的助产士,培训内容包括方案和数据收集、世界卫生组织基本新生儿护理(普遍预防措施和清洁、常规新生儿护理、复苏、体温调节、母乳喂养、袋鼠式护理、小婴儿护理和常见疾病)以及美国儿科学会新生儿复苏计划(深入的基础复苏)。在实施每门培训课程后的 3 个时期内收集数据。
共有 71689 名新生儿参加了 3 个研究时期。在接受 ENC 培训后,所有原因、7 日新生儿死亡率从每 1000 例活产 11.5 例死亡降至每 1000 例活产 6.8 例死亡(相对风险:0.59[95%置信区间:0.48-0.77];P<.001),因为与出生窒息和感染相关的死亡率有所下降。围产儿死亡率而非死产率下降。在对随访监测失访进行校正后,新生儿复苏计划培训后 7 日新生儿死亡率进一步下降。
对助产士进行 ENC 培训可降低低危诊所的 7 日新生儿死亡率。进一步深入的新生儿复苏基础培训可能会进一步降低死亡率。