在美国居住的南亚人代谢综合征的流行率。

Prevalence of metabolic syndrome in South Asians residing in the United States.

机构信息

Department of Physiological Nursing, School of Nursing, University of California, San Francisco, San Francisco, California 94304, USA.

出版信息

Metab Syndr Relat Disord. 2010 Oct;8(5):417-23. doi: 10.1089/met.2009.0097.

DOI:10.1089/met.2009.0097

PMID:20939706

Abstract

AIMS/HYPOTHESIS: The aim of this study was to define the prevalence of the metabolic syndrome and its component risk factors among individuals of South Asian origin living in the United States.

METHODS

We analyzed baseline data from 1,445 participants enrolled in a cohort study investigating risk factors for cardiovascular disease in South Asians. We defined the metabolic syndrome using the International Diabetes Federation criteria for waist circumference (>90 cm for men; >80 cm, women), triglycerides (>150 mg/dL), high-density lipoprotein cholesterol (HDL-C) (<40 mg/dL (men), < mg/dL (women)), blood pressure (>135/80 mmHg), and fasting glucose (>100 mg/dL).

RESULTS

The mean age was 43 +/-10 years, and 30% of participants were women. The prevalence of metabolic syndrome was 27% (31% men vs. 17% women, P < 0.05). Fifty-nine percent of the cohort had high waist circumference (58% men vs. 62% women, P = not significant [N.S.]), 47% had low HDL-C [46% men vs. 48% women (NS)], 19% had elevated triglycerides (23% men vs. 8% women, P < 0.05), 14% had hypertension (16% men vs. 9% women, P < 0.05), and 13% had elevated fasting glucose (18% men vs. 11% women, P < 0.05). The most common metabolic syndrome phenotype is low HDL-C with elevated triglycerides.

CONCLUSIONS

Although the prevalence of the metabolic syndrome is lower than previous reports of South Asians, the prevalence is still unacceptably high despite the presence of protective demographic factors.

摘要

目的/假设：本研究的目的是确定生活在美国的南亚裔个体中代谢综合征及其组成危险因素的流行率。

方法

我们分析了一项心血管疾病风险因素调查队列研究中的 1445 名参与者的基线数据。我们使用国际糖尿病联合会的腰围标准（男性>90 厘米；女性>80 厘米）、甘油三酯（>150mg/dL）、高密度脂蛋白胆固醇（HDL-C）[男性<40mg/dL，女性<mg/dL]、血压（>135/80mmHg）和空腹血糖（>100mg/dL）来定义代谢综合征。

结果

参与者的平均年龄为 43±10 岁，30%为女性。代谢综合征的患病率为 27%（男性为 31%，女性为 17%，P<0.05）。该队列中有 59%的人腰围较高（男性为 58%，女性为 62%，P=无统计学意义[NS]），47%的人 HDL-C 较低[男性为 46%，女性为 48%（NS）]，19%的人甘油三酯升高（男性为 23%，女性为 8%，P<0.05），14%的人患有高血压（男性为 16%，女性为 9%，P<0.05），13%的人空腹血糖升高（男性为 18%，女性为 11%，P<0.05）。最常见的代谢综合征表型是 HDL-C 低伴甘油三酯升高。