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南亚人心血管健康:文化适应健康教育计划改善心血管风险因素。

Heart health for South Asians: improved cardiovascular risk factors with a culturally tailored health education program.

机构信息

Kaiser Permanente Medical Center Santa Clara, Santa Clara, CA, United States.

出版信息

BMC Public Health. 2023 Apr 19;23(1):711. doi: 10.1186/s12889-023-15667-y.

Abstract

BACKGROUND/AIM: The Kaiser Permanente (KP) Northern California Heart Health for South Asians (HHSA) Program is a two-hour educational class that provides culturally relevant lifestyle and dietary recommendations to South Asian (SA) patients, in an effort to reduce their known disproportionate burden of cardiovascular (CV) disease. We evaluated the impact of the HHSA Program on CV risk factors and major adverse CV events (MACE).

METHODS

A retrospective cohort study identified 1517 participants of SA descent, ≥ 18 years old from 2006 to 2019. We evaluated the change in risk factors with program attendance (median follow up of 6.9 years) for systolic blood pressure (SBP), diastolic blood pressure (DBP), triglycerides (TG), LDL, HDL, BMI, and HbA1c. We also performed a propensity matched analysis to evaluate differences in MACE including stroke, myocardial infarction (MI), coronary revascularization, and all-cause mortality.

RESULTS

There were significant improvements in DBP, TG, LDL-c, HDL-c, BMI, and HbA1c at one year follow up and sustained improvements in DBP (-1.01mmHg, p = 0.01), TG (-13.74 mg/dL, p = 0.0001), LDL-c (-8.43 mg/dL, p = < 0.0001), and HDL-c (3.16 mg/dL, p = < 0.0001) levels at the end of follow up. In the propensity matched analysis, there was a significant reduction in revascularization (OR 0.33, 95% CI 0.14-0.78, p = 0.011) and mortality (OR 0.41, 95% CI 0.22-0.79, p = 0.008), and a trend towards reduction in stroke.

CONCLUSIONS

Our study demonstrates the efficacy of a culturally tailored SA health education program in improving CV risk factors and reducing MACE. The program highlights the importance and value of providing culturally tailored health education in primary CV disease prevention.

摘要

背景/目的:凯撒永久(KP)北加州南亚人心血管健康(HHSA)计划是一个两小时的教育课程,为南亚(SA)患者提供文化相关的生活方式和饮食建议,以努力减少他们已知的心血管疾病不成比例的负担。我们评估了 HHSA 计划对心血管危险因素和主要不良心血管事件(MACE)的影响。

方法

一项回顾性队列研究确定了 2006 年至 2019 年期间 1517 名年龄在 18 岁及以上的 SA 血统参与者。我们评估了课程出勤率对收缩压(SBP)、舒张压(DBP)、甘油三酯(TG)、低密度脂蛋白(LDL)、高密度脂蛋白(HDL)、体重指数(BMI)和糖化血红蛋白(HbA1c)的影响(中位数随访 6.9 年)。我们还进行了倾向匹配分析,以评估 MACE 包括中风、心肌梗死(MI)、冠状动脉血运重建和全因死亡率的差异。

结果

在一年随访时,DBP、TG、LDL-c、HDL-c、BMI 和 HbA1c 均有显著改善,DBP(-1.01mmHg,p=0.01)、TG(-13.74mg/dL,p=0.0001)、LDL-c(-8.43mg/dL,p<0.0001)和 HDL-c(3.16mg/dL,p<0.0001)在随访结束时水平持续改善。在倾向匹配分析中,血运重建(OR 0.33,95%CI 0.14-0.78,p=0.011)和死亡率(OR 0.41,95%CI 0.22-0.79,p=0.008)显著降低,中风有降低的趋势。

结论

我们的研究表明,针对南亚人群的文化适应性健康教育培训计划在改善心血管危险因素和降低 MACE 方面具有疗效。该计划强调了在初级心血管疾病预防中提供文化适应性健康教育的重要性和价值。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8961/10114338/3cc26f1131d0/12889_2023_15667_Fig1_HTML.jpg

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