Chirico G, Beccagutti F
Department of Neonatology and NICU, Spedali Civili, Brescia, Italy.
Minerva Pediatr. 2010 Oct;62(5):499-505.
The main functions of the nasal airway are respiration and olfaction. The nose and sinuses condition air before reaching the lower respiratory tract by providing almost 100% humidification, warming, filtering and trapping of foreign particles. The airway epithelium contributes to the host defense system. Any alteration of this clearance system may produce significant problems, particularly in neonates, who are obligate nasal breathers until they are at least two months old. Nasal obstruction, and the inability to remove nasal secretion by nose blowing, may have serious consequences, such as respiratory distress or discomfort, altered sleep cycle, increased risk of obstructive apnoea and feeding difficulties. Most cases of nasal obstruction in neonates and infants are due to generalized nasal airway obstruction associated with neonatal rhinitis, viral upper respiratory tract infections, and possibly milk/soy allergies. Saline nasal lavage is recommended as an adjunct therapy for rhinosinusitis and allergic rhinitis, and in most cases of nasal congestion or obstruction in newborns, infants and children. In two recent experiences, was deemed to be the Narhinel method safe and effective for treatment of nasal congestion in babies with viral infections of the upper respiratory tract, or for the prevention of acute otitis media (AOM) and acute rhinosinusitis (AR) in children. Due to the efficacy, ease of use, tolerability and the lack of alternative medications in children younger than 12 years of age, nasal irrigation with physiological saline solution, followed by gentle aspiration, represent an effective method for the prevention and control of nasal congestion or obstruction in term or preterm neonates, infants and children.
鼻气道的主要功能是呼吸和嗅觉。在空气到达下呼吸道之前,鼻子和鼻窦通过提供几乎100%的加湿、加热、过滤和捕获外来颗粒来调节空气。气道上皮有助于宿主防御系统。该清除系统的任何改变都可能产生严重问题,尤其是在新生儿中,他们在至少两个月大之前都是必须经鼻呼吸的。鼻塞以及无法通过擤鼻清除鼻腔分泌物可能会产生严重后果,如呼吸窘迫或不适、睡眠周期改变、阻塞性呼吸暂停风险增加以及喂养困难。新生儿和婴儿的大多数鼻塞病例是由于与新生儿鼻炎、病毒性上呼吸道感染以及可能的牛奶/大豆过敏相关的广泛性鼻气道阻塞。生理盐水鼻腔灌洗被推荐作为鼻窦炎和过敏性鼻炎的辅助治疗方法,以及用于大多数新生儿、婴儿和儿童的鼻塞或阻塞情况。在最近的两项经验中,Narhinel方法被认为对于治疗上呼吸道病毒感染婴儿的鼻塞或预防儿童急性中耳炎(AOM)和急性鼻窦炎(AR)是安全有效的。由于其有效性、易用性、耐受性以及12岁以下儿童缺乏替代药物,用生理盐水溶液进行鼻腔冲洗,随后轻柔抽吸,是预防和控制足月儿或早产儿、婴儿和儿童鼻塞或阻塞的有效方法。