大脑中动脉干闭塞患者缺血性病灶的区域分布动力学与侧支循环有关。
Dynamics of regional distribution of ischemic lesions in middle cerebral artery trunk occlusion relates to collateral circulation.
机构信息
Klinik und Poliklinik für Neurologie, Kopf- und Neurozentrum, Universitätsklinikum Hamburg-Eppendorf, Hamburg, Germany.
出版信息
J Cereb Blood Flow Metab. 2011 Jan;31(1):36-40. doi: 10.1038/jcbfm.2010.185. Epub 2010 Oct 13.
Abstract
We describe the regional distribution of acute perfusion, diffusion, and final infarct lesions in middle cerebral artery (MCA) trunk occlusion. A total of 31 patients with acute ischemic stroke and MCA trunk occlusion were studied by multiparametric magnetic resonance imaging. Probabilistic maps of lesion distribution were generated. The probability of initial and final infarcts was highest in the central MCA region with decreasing probability toward the periphery where the probability of the tissue at risk of infarction to be saved was highest. The probability of brain regions being involved in acute diffusion lesions and evolving into or escaping from the final infarct relates to the anatomy of arterial blood supply.
摘要
我们描述了大脑中动脉（MCA）主干闭塞时急性灌注、弥散和最终梗死病变的区域分布。通过多参数磁共振成像对 31 例急性缺血性脑卒中伴 MCA 主干闭塞患者进行了研究。生成了病变分布的概率图。初始和最终梗死的概率在 MCA 中央区域最高，向边缘逐渐降低，而边缘区域的梗死风险组织被挽救的概率最高。脑区发生急性弥散病变并发展为或逃避最终梗死的概率与动脉血供的解剖结构有关。
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