Department of Biomaterials, King's College London Dental Institute at Guy's, King's College and St. Thomas' Hospitals, King's College London, London, UK.
Clin Oral Investig. 2011 Dec;15(6):895-900. doi: 10.1007/s00784-010-0470-2. Epub 2010 Oct 13.
Unnecessary over-preparation of carious enamel often occurs clinically during operative caries management. The working hypothesis to be investigated in this study is the potential for bio-active glass air abrasion to remove selectively only demineralised enamel in artificial enamel lesions when compared to equivalent alumina air abrasion, so potentially minimising cavity over-preparation. Bisected artificial, paired smooth surface enamel lesions on ethics-approved, extracted sound human molars were created and subsequently air abraded with 27 μm alumina (n = 19) and bio-active glass (n = 19). The difference between pre-operative lesion boundary and post-operative cavity margin was calculated following optical confocal fluorescent assessment of the lesion boundary. Data indicated mean% over-preparation (sound enamel removal) of 176% with alumina and 15.2% for bio-active glass (p = 0.005). Bio-active glass abrasion removed completely the demineralised enamel from artificial lesions with clinically insignificant over-preparation of sound tissue, indicating technique selectivity towards grossly demineralised enamel. Alumina air abrasion resulted in substantial enamel removal in both sound and demineralised tissues indicating the operator selectivity required to use the techniques effectively in clinical practice.
临床上在进行龋齿治疗时,常常会过度预备有龋的牙釉质。本研究的假设是,与同等粒径的氧化铝喷砂相比,生物活性玻璃喷砂具有选择性去除人工釉质病损中脱矿牙釉质的潜力,从而潜在地最小化窝洞预备过度。将经过伦理批准的、从健康人磨牙上提取的成对的、人工的、光滑表面釉质病损对半切开,然后用 27μm 的氧化铝(n=19)和生物活性玻璃(n=19)进行喷砂处理。使用病变边界的光学共聚焦荧光评估后,计算术前病变边界和术后窝洞边缘之间的差异。数据显示,氧化铝的平均过度预备(去除健康牙釉质)为 176%,而生物活性玻璃为 15.2%(p=0.005)。生物活性玻璃喷砂可完全去除人工病变中的脱矿牙釉质,对健康组织的过度预备可忽略不计,表明该技术对明显脱矿的牙釉质具有选择性。氧化铝喷砂处理会导致健康组织和脱矿组织的大量牙釉质去除,这表明在临床实践中需要操作人员具有选择性才能有效地使用这些技术。