给喂食雄激素类似物米勃酮的鸡接种针对特定疾病的疫苗后的免疫情况。

Vaccination immunity to selected diseases in chickens fed the androgen analog mibolerone.

作者信息

Romero C H, Claflin W, Frank F, Chang T S, Purchase H G

出版信息

Poult Sci. 1978 Jan;57(1):74-9. doi: 10.3382/ps.0570074.

PMID:209430

Abstract

Chickens fed the androgen analog mibolerone during the first 7 weeks of life regress their bursa of Fabricius but can be properly immunized by vaccination against avian pathogens of major economic importance such as Newcastle disease virus, infectious laryngotracheitis virus, avian encephalomyelitis virus, infectious bronchitis virus, fowl pox virus, Marek's disease virus, and Pasteurella multocida, the pathogen causing fowl cholera. These findings on immunocompetence to infectious agents are important because we have previously shown that the administration of mibolerone prevents the development of lymphoid leukosis tumors.

摘要

在生命的前7周内喂食雄激素类似物米勃酮的鸡，其法氏囊会退化，但通过接种疫苗可对具有重大经济意义的禽类病原体进行有效免疫，这些病原体包括新城疫病毒、传染性喉气管炎病毒、禽脑脊髓炎病毒、传染性支气管炎病毒、鸡痘病毒、马立克氏病病毒以及引起禽霍乱的多杀性巴氏杆菌。这些关于对感染因子免疫能力的发现很重要，因为我们之前已经表明，米勃酮的给药可预防淋巴白血病肿瘤的发生。