Yan Hui, Deng Xue-Mei, Wu Chang-Xin
College of Animal Science and Technology, China Agricultural University, Beijing, China.
Yi Chuan. 2010 Oct;32(10):1051-6.
The balancers of Drosophila melanogaster are widely used in genetic research. By analyzing the phenotype of offspring from hybridization of chapped wing (L) mating with OR, 982p and e, respectively, we mapped the chapped wing mutation on chromosome 3 for the first time and demonstrated the chapped wing mutation as a new balancer of D. melanogaster with dominant wing nicking phenotype. Finally, we bred a novel gathering line with double balancers of L and Cy in D. melanogaster. The mutant L provided a legible dominant marker for the balancer of chromosome 3, and the cultivation of double balancers chapped-curly wing enriches the balancer stock, which is often used in mapping and screening.
黑腹果蝇的平衡子在遗传学研究中被广泛应用。通过分别分析裂翅(L)与OR、982p和e杂交后代的表型,我们首次将裂翅突变定位到3号染色体上,并证明裂翅突变是一种具有显性翅刻痕表型的黑腹果蝇新平衡子。最后,我们培育出了一种具有L和Cy双平衡子的新型黑腹果蝇品系。突变体L为3号染色体的平衡子提供了一个清晰的显性标记,裂翅-卷翅双平衡子的培育丰富了平衡子品系,其常用于基因定位和筛选。